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Reproductive Hormone
M.B
| Term | Definition |
|---|---|
| Length of Oestrous Cycle For: Cow | 21 Days |
| Length of Oestrous Cycel for: Ewe | 17days |
| Length of Oestrous Cycel for: Sow | 20 Days |
| Length of Oestrous Cycel for: Mare | 22 Days |
| Length of Oestrous Cycel for: DOe | 20 Days |
| Length Of Menstrual Cycle For: Humans | 28 Days |
| Main Hormone of Oestrous Cycle (6) | 1) FSH (Follicle Stimulating Hormone) 2) E2 (Oestrogen) 3) LH (Luteinising Hormone) 4) P4 (Progesterone) 5) PGF2 Alpha (Prostaglandin) 6) GnRH |
| FSH (Follicle Stimulating Hormone | -Stimulates Small ovarian Follicles to Grow -Stimulates Oestrogen Secretion From Large Follicles |
| E2 (Oestrogen) (Peak) | -Prep Uterus & Vagina For Mating & Breeding-V Cornified-Vulva Red, swell, odur -Inh Follicle Gw-Promote follicle Atresia - Behavioural Oestrus= "Heat" -Inc & Thickens Cervical Mucus -Stim Pituitary release LH -Stim retrograde Uterine Contractions |
| LH (Luteinizing Hormone) | -Stim thecal cells to produce ANDROGENS -Causes Ovulation (Graafian Follicle Bursts releasing the Ovum -Stim the Remnants of the burst follicle to form a corpus Luteum (Luteinisation) -Stim Corpus Luteum to Sec P4 (Progesterone) |
| P4 (Progesterone) | -Develops Endometrium in prep-Pregnancy -Dec Cervical Mucus Sec -Prev Uterine Contractions -Causes Devel of Cervical Plug -Supp behavioural oestrus -Inhib Follicle Growth -Sensitises the Brain to E2 -Inh Immune- Uterus -Aid Mammogenesis |
| GnRh | -Controls the Secretion of Gonadotrophins (FSH & LH) by changing Frequency of GnRH secretion |
| PGF2Alpha | -Destroys Corpus Luteum (Luteolysis) |
| Menstrual Cycle | -No Oestrus -(Brain does not respond to E2 -Starts with Menses (Period/Bleeding) |
| Estrous Cycle | -No Menstration -Bleeding -Starts with Oestrus |
| 2 Phases | -Follicular Phase -Luteal Phase |
| What occurs in Follicular Phase For Menstrual Cycle | -Bleeding -Estradiol -Start of Ovulation |
| What occurs in Luteal Phase for Menstrual Cycle | -End of Ovulation -Progesterone -Luteolysis |
| What occurs in the Luteal Phase for Estrous Cycle | -(Beg) Estrus Ovulation -Progesterone (middle) -Estradiol (Middle) -Luteolusis (End) |
| Menstrual Cycle compared with Estrus Cycle | -Similar Hormone Profile when placed on top of each other |
| Menstrual Cycle Start at | Menses (Bleeding) |
| Estrus Cycle Starts at | Estrus |
| What happens when A cycling Female is treated with FSH | -Small Ovarian Follicles will be stimulated to grow -More Follicles will be recruited in each follicle wave -Dep on time and dose many follicles will grow-Superovulation -used in transfer programs -Treatment of fertility problems |
| What if a Cycling female eats continual small doses of Oestrogen? | -Cycling will be prevented -FSH will not be secreted -Ovulation will not occur -Bases of Contraception Pill -To avoid reduced fertility should not eat these foods -Plastic Derivatives and Soy |
| What if a cycling female eats continual large amounts of foods containing oestrogen | -Cycling will be prevented -FSH will not be secreted -Ovulation will not occur -Exhibit Constant symptoms of Estrus (HEAT) -Red Clover should be avoided during mating |
| What will happen if a cycling female is treated with PGF2 Alpha | -If the female is in the Follicular phase, there will be no effect -If the female is in the Luteal phase, Luteolysis will occur, followed 1-3 days later by the beginning of a new cycle -Used for Synchronizing Cycles for mating |
| Pregnancy Hormone (7) | 1) Progesterone (P4) 2) CRH 3) ACTH 4) Cortisol 5) Oestrogen (E2) 6) Prostaglandin (PGF2 Alpha 7) Oxytocin |
| Progesterone (Preg) | -Prevents Uterine Contractions -Suppresses Oestrus |
| CRH (Preg) | -Produced by fetal hypothalamus -Stim ACTH Secretion |
| ACTH (Preg) | -Secr by Pituitary Gland -Stim Cortisol Secretion |
| Cortisol (Preg) | -Secreted by Adrenal Gland & Travel in the blood to the placenta -Causes placenta to stop producing P4 and to Convert P4 to E2 -Stim Uterine Production of PGF2 Alpha |
| Oestrogen (E2) (Preg) | -E2 upregulates Oxytocin receptors on the myometrium |
| Prostaglandin (PGF2Alpha) (Preg) | -Transferred to Ovarian Artery by counter-current exchange -Causes Luteolysis -When All P4 is gone, nothing to prevent contractions |
| Oxytocin | -Stim Contractions -PGF2Alpha & Oxytocin Amplify Contractions by Positive Feedback loop -Labour -Milk Let Down |
| What will happen if a pregnant female is treated with PGF2Alpha | -If the Dose is Sufficient, Luteolysis will occur, followed by abortion or birth -If all sources of progesterone are removed- nothing to Stop uterine contractions -PGF2Alpha will begin a cyclical effect with oxytocin, each stim Uterine Contractions |
| How Might premature births be prevented or delayed? | -Prevent the synthesis of PGF2Alpha -The enzyme (cox2)catalyses the conversion of Arachidonic Acid to Prostaglandin -Administer Progesterone -Prevents Upregulation of Oxytocin receptors on Uterus |
| Teasers | -To identify Heat -Female stayes to be mated is on heat -If pushes Male off not on heat |
| Intrinsic NS | -Peristalsis |
Created by:
Melissa Jones
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