Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
USMLE
MSK Derm 3
| Question | Answer |
|---|---|
| Cause of Green Nail Syndrome | P.aeurginosa usually acquired by prolonged exposure to water |
| Superficial papules and pustules with erythematous halo on parts of body that are covered by shorts | Hot Tub Folliculitis |
| Erythematous macule infarction bullae ulcer; a/w fever, chills, and tenderness in hospitalized/ immunocompromised patients | Ecthyma Gangrenosum |
| Painless ulcer/chancre @ site of inoculation; Hard, clean edge with a yellowish base | Primary Syphilis |
| Firm macules and papules that are pink, brownish-red; Scaly macules on palm; condyloma lata | Secondary Syphilis |
| Plaques and nodules with scars healed in center with/without scales and with/without ulceration | Tertiary Syphilis |
| Jarish-Herxheimer Syndrome | Flu-like symptoms within first 24 hours of treatment of syphillis; Normal process caused by lysing of spirochetes |
| Condyloma acuminatum | Verrucae (warts) in genital region |
| Flat to convex papules with rough, pebble-like surface | Verrucae (warts) |
| Cause of Molluscum Contagiosum | poxvirus |
| Firm, umbilicated (dent in the center), dome- shaped papules, shiny; Pruritic | Molluscum Contagiosum |
| How is latency formed w/ Herpes simplex virus | Virus ascends in peripheral sensory nerves and enters dorsal root ganglia where latency is established |
| Groups of small vesicles and shallow ulcers on erythematous base (pustules erosions crust) | Typical herpes lesions |
| Patches of erythema, small erosions, fissures, or subclinical lesions | Atypical herpes lesions |
| "Dewdrops on a rose petal" | Herpes Zoster |
| Erythematous/Edematous base with superimposed clear vesicles w/ unilateral dermatome distribution | Herpes Zoster |
| Most common dermatophyte infection | Trichophyton rubrum |
| MCC of Tinea Capitas | Trichophyton tonsurans |
| Athlete's foot | Tinea Pedis |
| Dermatophyte infection on scalp | Tinea Capitas |
| Dermatophyte infection on face | Tinea Facialis |
| Dermatophyte infection in inguinal region | Tinea Cruris |
| Dermatophyte infection on trunk/extremities | Tinea Corporis |
| Dermatophyte infection on hand | Tinea Manuum |
| Dermatophyte infection from pets | Microsporum canis |
| sharply demarcated, polycyclic, erythematous, eroded patches with small pustular lesions; base can be scraped away w/ gauze | Candidiasis |
| Cause of Pityriasis (tinea) versicolor | Malassezia furfur |
| Well-demarcated scaling patches with variable pigmentation; Macules that are sharply marginated, round/oval in shape, with varying size | Pityriasis (tinea) versicolor |
| "Spaghetti and meatballs" appearance on KOH stain | Pityriasis (tinea) versicolor |
| Cause of scabies | Sarcoptes scabiei mite |
| Gray/skin-colored ridges from 5mm to 10cm in length | Scabies |
| Cause of Pediculosis | The arthropod Phthirus |
| Hair lice | Pediculosis caused by Phthirus Humanus capitas |
| Genital crabs | Pediculosis caused by Phthirus pubis |
| Tx of Acne vulgarus | Tretinoin/Adapalene(retenoids) & Tetracyclines |
| Tx for Gadolinium induced systemic sclerosis | Phototherapy |
| Topical agent used to treat S. aureus and most Strep except group D | Mupirocin |
| Topical agent used to treat dermatophyte infections | Griseofulvin |
| Topical/oral agent used to treat dermatophyte infections | Terbinafine (an allylamine) |
| Topical agent that is very effective on yeasts | Nystatin |
| Tx of ectoparasites | Permethrin (preferred tx) & Lindane (not used as much due to neurotoxicity) |
| Tx of psoriasis | Methotrexate(antimetabolite) & Cyclosporin (Calcineurin inhibitor) |
| Topical Tx of actinic keratosis, Bowens disease and superficial basal cell carcinoma | 5-fluorouracil |
| Tx of atopic dermatitis | Tacrolimus & Pimecrolimus(mild to moderate cases) Both are calcineurin inhibitors |
| Patients on Calcineurin inhibitors must do what? | Wear sunscreen when outside due to cutaneous immunosuppresion that could lead to skin cancer |
| Biological agent that binds 2 molecules of TNF | Etanercept |
| Biological agent that binds to the TNF receptor | Infliximab |
| MCC of dwarfism | Achondroplasia |
| Cause of Achondroplasia | defect in a fibroblast growth factor receptor protein (FGFR3) Found on chrom 4 |
| MCC of osteomyelitis | S. aureus |
| MCC of osteomyelitis a/w GU infections | E. Coli, Pseudomonas, Klebsiella |
| MCC of osteomyelitis a/w drug abuse | E. Coli, Pseudomonas, Klebsiella |
| MCC of osteomyelitis in neonates | H. Influenzae and Group B Strep |
| MCC of osteomyelitis in pt's w/ sickle cell disease | Salmonella |
| Pott's disease | Tuberculosis osteomyelitis involving the spine |
| Muscle disease w/ LMN signs | Poliomyelitis |
| Muscle disease w/ both UMN & LMN signs | Amyotrophic lateral Sclerosis |
| Muscle disease seen in infants ("floppy baby") | Werdnig-Hoffmann disease |
| Symmetric ascending muscle weakness beginning in distal and lower extremities | Guillain-Barre Disease |
| Genetics of Duchenne Muscular Dystrophy | X-linked recessive Complete absence of dystrophin gene |
| Genetics of Becker’s Muscular Dystrophy | X-linked recessive Mutation causing production of truncated dystrophin |
| Defect in Oculopharyngeal dystrophy | PABPN1(Poly-A binding protein, nuclear 1) gene on chrom 14 GCG trinucleotide expansion |
| Defect in limb-girdle dystrophy | Mutation of laminin |
| Defect in Emery-dreifuss dystrophy | Mutation of emerin(X-linked) Less commonly, mutation of laminin |
| Defect in myotonic dystrophy | DMPK (dystrophila myotonia-protein kinase) gene on chrom 19 CTG trinucleotide expansion |
| Defect in Nemaline myopathy | ACTA 1 gene on chrom 1; threadlike; dark inclusions of Z-band material in type I fibers |
| Defect in Central Core Disease | RYR 1 gene on chrom 19; codes for a calcium release channel; a/w malignant hyperthermia |
| Kearns-Sayre Syndrome | Ophthalmoplegia plus retinal pigmentary degeneration and complete heart block Caused by large deletion of mitochondrial DNA |
| Dermatomyositis | Heliotrope rash with periorbital edema; Muscle weakness; myocarditis; interstitial lung dx, 40% have cancer too |
Created by:
Asclepius
Popular USMLE sets