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Histology

Respiratory System Development

QuestionAnswer
The respiratory diverticulum appears as an outgrowth of the what? Ventral wall of the foregut
Location of the respiratory system is determined by the transcription factor...? TBX4 (expressed in the endoderm of the gut tube)
TBX4 induces what? Formation of the bud and continued growth and differentiation of the lungs.
Epithelium of the larynx, trachea, bronchi and the rest of the lungs is entirely of what origin? Endodermal
The cartilaginous, muscular and connective tissue components of the trachea and lungs are derived from what? Splanchnic mesoderm
Cartilages and and muscles of the larynx originate from the mesenchyme of what? 4th and 6th pharyngeal arches
4th arch derivatives of the larynx is innervated by what? Superior laryngeal nerve
Derivatives of the 6th arch of the larynx is innervated by what? Recurrent laryngeal nerve
Splanchnic mesoderm covering the body wall becomes the what? parietal pleura
Mesoderm covering the outside of the lung develops into the what? visceral pleura
Respiration becomes possible when? Bronchiole-lining cells become flat and associate with blood capillaries.
Mature alveoli are not present when? Before birth
Surfactant is produced by what? Type II alveolar epithelial cells
Aspiration of amniotic fluid does what 2 things? Stimulates lung development and conditions breathing muscles.
Abnormalities in the partitioning of the esophagus and the trachea by the tracheoesophogeal septum is associated with what defects? Esophageal atresia and tracheoesophageal fistulas
Esophageal atresia and tracheoesophageal fistulas are associated with what other complications? VACTERL vertebral abnormalities, anal atresia, cardiac defects, tracheoesophageal fistulas, esophageal atresia, renal anomalies limb defects
Gastric contents that enter the trachea and lungs can cause what 2 problems? Pneumonitis and pneumonia
Created by: shuckybean
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