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Histology
Lymphatic system
| Question | Answer |
|---|---|
| Any substance that can induce a specific immune response is called a what? | Antigen |
| Nonspecific immune responses are called? | Innate |
| Specific immune responses are called? | Adaptive |
| Humoral response produces what? | Antibodies |
| The chief cellular constituents of the lymphatic system are the what? | Circulating lymphocytes |
| T-lymphocytes mature where? | Thymus |
| ________ T-lymphocytes interact with other cells to initiate immune responses. | Helper CD4+ |
| ________ T-lymphocytes kill target cells. (ie virus infected cells, cancer cells, etc) | Cytotoxic CD8+ |
| __________ differentiate in the bone marrow and participate in humoral immunity. | B-lymphocytes |
| What lymphocytes are specialized to kill transformed cells? | NK lymphocytes |
| Immunocompetent lymphocytes undergo __________ in secondary lymphoid tissues. | antigen dependent activation |
| Initial response to an antigen is what? | Inflammation |
| First encounter with an antigen uses what type of antibodies? | IgM |
| Secondary immune response uses what type of antibodies? | IgG |
| What are the 2 types of immune responses? | Humoral and cell mediated |
| Helper/cytotoxic T cells recognize and bind to antigens that are bound to what? | MHC molecules |
| What are the 2 classes of MHC molecules? | Class I and class II |
| What class of MHC molecules are present in all nucleated cells? | Class I |
| What class of MHC molecules are present on antigen presenting cells? | Class II |
| MHC I interact only with what? | CD8+ T cells |
| MHC II interact with only what? | CD4+ T cells |
| Lymphatic tissue that guards the alimentary tissue, respiratory passages and genitourinary tract is called what? | MALT (mucosa-associated lymphoid tissue) |
| Secondary nodules contain what that indicates an immune response is taking place? | Germinal center |
| Germinal centers are sites of what? | Proliferation and differentiation of lymphocytes, differentiation of plasma cells and production of antibodies. |
| Aggregations of nodules are usually seen in what 3 locations? | Tonsils, Peyer's patches,Vermiform appendix |
| Tonsils form a ring at the entrance of the what? | Oropharynx (Waldeyer's ring) |
| What are the 3 types of lymph node sinuses? | Subcapsular sinus, Trabecular sinus, Medullary sinus |
| Where to do lymphocytes enetr the node from the blood? | HEV (high endothelial venules) |
| Lymphocytes leave the node through what? | Efferent lymphatic vessels |
| Thymic medulla contains what unique feature? | Hassall's corpuscles |
| Hassall's corpuscles are what? | Concentrically arranged epithelioreticular cells |
| What prevents antigens from reaching the T cells? | Blood-thymus barrier |
| Components of the blood-thymus barrier are? | Endothelium, Basal lamina, Macrophages, Epithelioreticular cells |
| Thick accumulations of lymphocytes surrounding an artery is called what? | White pulp |
Created by:
shuckybean
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