Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

USMLE

MSK 2

QuestionAnswer
Heberden's nodes (DIP) and Bouchard's nodes (PIP) osteoarthritis
pain in weight-bearing joints after use that improves with rest osteoarthritis
destruction of articular cartilage, subchondral bone formation, sclerosis, osteophytes, and eburnation are associated with what? osteoarthritis
what are joint mice? what are they associated with? osteophytes that fracture and float into synovial fluid along with fragments of separated cartilage - seen in osteoarthritis
pannus formation in joints, especially MCP, PIP rheumatoid arthritis
morning stiffness improving with use; symmetric joint involvement, and systemic symptoms (fever, fatigue, pleuritis, pericarditis) rheumatoid arthritis
Rx for severe cases of osteoporosis? bisphosphonates or pulsatile PTH
type I osteoporosis? postmenopausal - increased bone resorption due to decreased estrogen levels
type II osteoporosis? senile osteoporosis - affects men and women over 70
what types of fractures are associated with type I osteoporosis? vertebral crush fractures - acute back pain, loss of height, kyphosis
what type of fractures are associated with type II osteoporosis? distal radius (Colles') fractures, vertebral wedge fractures
in this disease there is a failure of normal bone resorption that leads to thickened, dense bones osteopetrosis (marble bone disease)
in this disease osteoclasts function abnormally osteopetrosis
what level of alk phos is osteopetrosis associated with? normal
what causes osteitis fibrosa cystica? hyperparathyroidism
this disease is characterized by 'brown tumors', high serum calcium, low serum phosphorus, and high alk phos osteitis fibrosa cystica
these are cystic spaces lined by osteoclasts, filled with fibrous stroma and sometimes blood brown tumors (seen in osteitis fibrosa cystica)
in this disease there is abnormal bone architecture caused by an increase in both osteoblastic and osteoclastic activity Paget's disease (osteitis deformans)
what level of alk phos is Paget's disease associated with? increased (normal serum calcium, phosphorus, adn PTH)
in this disease, bone is replaced by fibroblasts, collagen, and irregular bony trabeculae polyostotic fibrous dysplasia
Albright's syndrome is a form of what? polyostotic fibrous dysplasia
multiple unilateral bone lesions, unilateral ppigmented skin lesions, precocious puberty Albright's syndrome
pain and stiffness in shoulders and hips, often with fever, malaise and weight loss; doesn't cause muscular weakness polymyalgia rheumatica
what is polymyalgia rheumatica associated with? temporal (giant cell) arteritis; occurs in patients over 50
is ESR increased or decreased in polymyalgia rheumatica? increased
progressive proximal muscle weakness caused by CD8+ T cell-induced injury to myofibers polymyositis
muscle biopsy with evidence of inflammation is diagnostic for what? polymyositis
increased CK, increased aldolase, and positive ANA, anti-Jo-1 polymyositis/dermatomyositis
Raynaud's, arthralgias, myalgias, fatigue, esophageal hypomotility mixed CT disease
antibodies to U1RNP? mixed connective tissue disease
what is the classic triad of Sjogren's syndrome? xerophthalmia, xerostomia, arthritis
patients with Sjogren's syndrome are at increased risk for what? B cell lymphoma
what is enlarged in Sjogren's syndrome? parotids
what patients does Sjogren's primarily affect? females between 40-60
autoantibodies to ribonucleoprotein antigens, SS-A (Ro), SS-B (La) Sjogren's
fever, fatigue, weight loss, nonbacterial verrucous endocarditis, hilar adenopathy, and Raynaud's SLE
what are the kidney findings in SLE? wire loop lesions in kidney with immune complex deposition (with nephrotic syndrome)
what part of the SI does celiac sprue tend to affect? jejunem
what skin finding is celiac sprue associated with? dermatitis herpetiformis
what malignancy is celiac sprue most strongly affiliated with? T cell lymphoma
blunting of villi and lymphocytes in the lamina propria are suggestive of what? celiac sprue
Created by: Asclepius