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USMLE

Cell Bio/Histo/Path -6

QuestionAnswer
Association for tumor marker: PSA Screening for Prostatic Carcinoma
Association for tumor marker: CEA -Carcinoembryonic antigen. -In ~70% of colorrectal and pancreatic cancers -Also produced by gastric and breast carcinomas -Very nonspecific
Association for tumor marker: alpha-fetoprotein -Hepatocellular carcinomas -Nonseminomatous germ cell tumors of the testis (eg yolk sac tumor)
Association for tumor marker: beta-hCG -Hydatidiform moles -Choriocarcinomas -Gestational trophoblastic tumors
Association for tumor marker: CA-125 Ovarian malignant epithelial tumors
Association for tumor marker: S-100 -Melanoma -Neural tumors -Astrocytomas
Association for tumor marker: Alkaline phosphatase -Metastases to bone -Obstructive biliary disease -Paget's disease of bone
Association for tumor marker: Bombesin -Neuroblastoma -Lung cancer -Gastric cancer
Association for tumor marker: TRAP -Tartrate-resistance acid phosphatase -Found in hairy cell leukemia
What type of cell is found in hairy cell leukemia? B-cells
Association for tumor marker: CA-19-9 Pancreatic adenocarcinoma
Tumor marker for: Prostatic carcinoma -PSA -Prostatic acid phosphatase
Tumor marker for: Colorectal cancer CEA - Carcinoembryonic antigen -Produced by 70% of colorectal cancers
Tumor marker for: Pancreatic cancer CEA - Carcinoembryonic antigen -Produced by 70% of pancreatic cancers CA-19-9 -Produced in pancreatic adenocarcinoma
Tumor marker for: Gastric carcinoma -CEA - Carcinoembryonic antigen -Bombesin
Tumor marker for: Breast carcinoma CEA - Carcinoembryonic antigen
Tumor marker for: Hepatocellular carcinoma alpha-fetoprotein
Tumor marker for: Nonseminomatous germ cell tumors of the testis alpha-fetoprotein
Tumor marker for: Hydatidiform moles beta-hCG
Tumor marker for: Choriocarcinoma beta-hCG
Tumor marker for: Gestational Trophoblastic tumors beta-hCG
Tumor marker for: Malignant ovarian epithelial tumors CA-125
Tumor marker for: Melanoma S-100
Tumor marker for: Neural tumors General: S-100 Neuroblastoma: Bombesin
Tumor marker for: Astrocytomas S-100
Tumor marker for: Metastases to bone Alkaline phosphatase
Tumor marker for: Obstructive biliary disease Alkaline phosphatase
Tumor marker for: Paget's disease of bone Alkaline phosphatase
Tumor marker for: Neuroblastoma Bombesin
Tumor marker for: Lung cancer Bombesin
Tumor marker for: Hairy cell leukemia TRAP (Tartrate-resistant acid phosphatase)
Tumor marker for: Pancreatic adenocarcinoma CA-19-9
Cancer associated with: HTLV-1 HTLV=Human T-Lymphotropic Virus Adult T-cell leukemia
Cancer associated with: HBV Hepatocellular carcinoma
Cancer associated with: HCV Hepatocellular carcinoma
Cancer associated with: EBV -Burkitt's lymphoma -Nasopharyngeal carcinoma
Cancer associated with: HPV -Cervical carcinoma (with HPV 16,18) -Penile/anal carcinoma
Cancer associated with: HHV-8 HHV-8 = Kaposi's sarcoma-associated herpes virus -Kaposi's sarcoma -body cavity fluid B-cell lymphoma
Oncogenic virus associated with: Adult T-cell leukemia HTLV-1 (HTLV=Human T-Lymphotropic Virus)
Oncogenic virus associated with: Hepatocellular carcinoma -HBV -HCV
Oncogenic virus associated with: Burkitt's lymphoma EBV
Oncogenic virus associated with: Nasopharyngeal carcinoma EBV
Oncogenic virus associated with: Cervical carcinoma HPV 16 and 18
Oncogenic virus associated with: Penile carcinoma HPV
Oncogenic virus associated with: Anal carcinoma HPV
Oncogenic virus associated with: Kaposi's sarcoma HHV-8 (aka Kaposi's sarcoma-associated herpesvirus)
Oncogenic virus associated with: body cavity fluid B-cell lymphoma HHV-8 (Human Herpesvirus 8)
Organ affected by: Aflatoxins Liver (hepatocellular carcinoma)
Organ affected by: Vinyl chloride Liver (angiosarcoma)
Organ affected by and effects of: CCl4 Liver -centrilobular necrosis -fatty change
Organ affected by: Nitrosamines -Esophagus -Stomach
Organ affected by: Cigarette smoke -Larynx -Lung
Organ affected by: Asbestos Lung -Mesothelioma -Bronchogenic carcinoma
Organ affected by: Arsenic Skin (squamous cell carcinoma)
Organ affected by: Naphthalene (aniline) dyes Bladder (transitional cell carcinoma)
Organ affected by: Alkylating agents Blood (leukemia)
Created by: Asclepius