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New FA Micro 7

hepatitis RNA picornavirus HAV
hepatitis DNA hepadnavirus HBV
hepatitis RNA flavivirus HCV
hepatitis delta virus HDV
hepatitis RNA calcivirus HEV
how is HAV trasmitted? fecal-oral
type of hepatitis that is transmitted enterically and causes water-borne epidemics HEV
defective virus that requires HBsAg as its envelope HDV
common cause of transfusion-mediated hepatitis HCV
best test to detect active hepatitis A? IgM HAVAb
continued presenc of what indicates carrier state of HBV? HBSAg
provides immunity to HBV HBsAb
positive during the window period of HBV HBcAb
HBV vaccination - what serologic marker is seen? HBsAb only
rectangular nucleocapsid protein of HIV? p24
HIV envelope proteins? gp41 and gp120
what crosses placenta in HIV infected mothers anti-gp120
CXCR1 mutation rapid progression to AIDS
CCR5 mutation homozygous - immunity (1% U.S. caucasians), heterozygous - slower course (20% U.S. caucasians)
infectious agents that don't contain DNA or RNA, just protein prions
normal prions have what? pathologic prions are what? normal - alpha helix, pathologic (like CJD) - beta pleated sheets
virus family of HPV? papovavirus
aseptic meningitis, herpangina - febrile pharyngitis, hand, foot, and mouth disease, myocarditis coxsackievirus - picornavirus
rotavirus belongs to what family? reovirus - DS linear segmented RNA
hemorrhagic fever, pneumonia, RDS in NM, AZ, CO, UT hantavirus - member of bunyavirus family (SS circular RNA; helical capsid)
ebola/marburg are what types of viruses? filoviruses - SS linear RNA, helical capsid
triad of cutaneous hemorrhages, deafness, and periventricular CNS calcifications in a neonate congenital CMV infection
virulence factor of staph aureus - binds Fc-IgG, inhibiting complement fixation and phagocytosis protein A
superantigen that binds to MHC II and TCR, resulting in polyclonal T cell activation TSST - (staph aureus)
what makes coagulase? staph aureus
antibody to what enhances host defenses against strep pyogenes? M protein
group A beta-hemolytic strep? strep pyogenes
what detects recent strep pyogenes infections? ASO titer
associated with rusty sputum, sepsis in sickle cell, and splenectomy? strep pneumo
most common cause of meningitis, otitis, pneumonia, sinusitis? strep pneumo
what gives immunity to strep pneumo? IgG antibodies to surface acidic polysaccharide
causes pneumonia, meningitis, and sepsis mainly in babies group B strep (agalactiae) - beta hemolytic, bacitracin resistant
what is Lancefield grouping based on? differences in the C carbohydrate on the bacterial cell wall
what can grow in 6.5% NaCl enterococci
enterococci can cause what? UTI, subacute endocarditis, biliary tract infections
bacteria related to colon cancer? strep bovis
type of strep viridans that can cause subacute bacterial endocarditis? strep sanguis
what does C. perfringens produce? alpha toxin
gram-positive rods with metachromatic granules? corynebacterium diphtheriae
woolsorter's disease? bacillus anthracis
inhalation of anthrax spores? flulike symptoms that rapidly progress to fever, pulmonary hemorrhage, and shock
gram-positive anaerobe that causes oral/facial abscesses that may drain through sinus tracks in skin actinomyces
gram positive, weakly-acid fast aerobe that causes pulmonary infection in immunocomprimised patients nocardia asteroides
sulfur granules actinomyces
gram-positive rods forming long branching filaments resembling fungi actinomyces & nocardia
most invasive disease of H. flu is caused by what capsular type? B
treatment for H. flu meningitis? ceftriaxone
treatment for neisseria gonorrhea? ceftriaxone - also z pack or doxycycline because 50% will also be infected with chlamydia
why don't you want to culture if pt. has epiglottitis? manipulation cause laryngeal spasm
members of enterobacter family (7) e. coli, salmonella, shigella, klebsiella, enterobacter, serratia, proteus
what antigen is related to the virulence of enterobacter? K antigen
all of these ferment glucose and are oxidase negative enterobacter
these bacteria grow pink colonies on MacConkey's agar citrobacter, klebsiella, e. coli, enterobacter (CEEK)
Created by: Asclepius