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New FA Micro 6

all DNA viruses except what are dsDNA? parvoviridae (part-of-a-virus)
all DNA viruses are linear except what? papovaviruses (circular, supercoiled), hepadnaviruses (circular, incomplete)
name 3 naked RNA viruses? calcivirus, picornavirus, reovirus (naked CPR)
this type of virus acquires envelopes from the nuclear membrane herpesvirus
most enveloped viruses aquire their envelope from where? from plasma membrane when they exit from cell
all viruses are haploid except what? retroviruses, which have 2 identical ssRNA molecules (diploid)
all DNA viruses replicate where? what is the exception? nucleus - except poxvirus
all RNA viruses replicate where? what are the exceptions? cytoplasm - except influenza and retroviruses
name the DNA viruses HHAPPPy viruses: hepadna, herpes, adeno, pox, parvo, papova
this DNA virus carries its own DNA-dependent RNA polymerase poxvirus
all DNA viruses are icosahedral except what? pox (complex)
naked DNA viruses (3) PAP: parvo, adeno, papova
enveloped DNA viruses (3) HPH: hepadna, pox, herpes
what is the largest DNA virus? poxvirus
virus causing febrile pharyngitis, pneumonia, conjunctivitis adenovirus
virus causing aplastic crises in sickle cell disease, fifth disease, hydrops fetalis? parvovirus
what is the smallest DNA virus? parvovirus (ss linear)
HBV is a member of what virus family? hepadnavirus - DNA, partial circular
members of the picornavirus family? "PERCH:" poliovirus, echovirus, rhinovirus, coxackievirus, HAV
HEV and Norwalk virus belong to what family? calciviruses - RNA (ss, linear), icosahedral
virus causing roseola (exanthem subitum) HHV-6
virus related to Kaposi's sarcoma? HHV-8
what type of virus is JC - causes PML in HIV papovavirus
type of virus causing Colorado tick fever? reovirus
number one cause of fatal diarrhea in kids? rotavirus
togaviruses (3)? rubella, EEE, WEE
flaviviruses (5)? HCV, yellow fever, dengue, St. Louis encephalitis, West Nile virus
to what family does influenza virus belong? orthomyxovirus
paramyxoviruses (4) PaRaMyxovirus: parainfluenza (croup), RSV, measles, mumps
Rx for RSV bronchiolitis in kids? ribavirin
what type of virus is rabies? rhabdovirus
what type of virus is HDV? deltavirus
MMR, Sabin polio, VZV, yellow fever, smallpox, and adenovirus have what type of vaccine? live attenuated
rabies, infulenza, HAV, and Salk polio are what type of vaccine? killed
egg-based vaccines? "FRY an egg:" flu, MMR, Yellow fever
the vaccine for what is recombinant? HBV- antigen is recombinant HBsAg
exchange of genes between 2 chromosomes by crossing over within regions of significant base sequence homology recombination
when viruses with segmented genomoes (e.g. influenza) exchange segments. high-frequency virus recombination; cause of worldwide pandemics reassortment
when 1 of 2 viruses that infect the cell has a mutation that results in a nonfunctional protein; the nonmutated virus complemetns the mutated one by making a functional protein that serves both viruses complementation
genome of virus A can be coated with the surface proteins of virus B; type B protein coat determines the infectivity of the phenotypically mixed virus; however, the progeny from this infection has a type A coat and is encoded by type A genetic material phenotypic mixing
DNA enveloped viruses (3) herpesvirus, HBV, smallpox
DNA nucleocapsid viruses (3) adenovirus, papillomaviruses, parvovirus
influenza virus, parainfluenza, RSV, measles, mumps, rubella, rapies, HTLV, and HIV are what type of RNA viruses? RNA enveloped viruses
enteroviruses (poliovirus, coxsackie virus, echovirus, HAV), rhinovirus, and reovirus are what type of RNA viruses? RNA nucleocapsid
segmented viruses? all are RNA viruses: "BOAR": bunyaviruses, orhtomyxoviruses, arenaviruses, and reoviruses
all paramyxoviruses have 1 serotype except what? parainfluenza virus - has 4
parainfluenza, mumps, measles, and RSV all belong to what family? paramyxoviruses
parotitis, orchitis, and aseptic meningitis? mumps
bluish-gray spots on buccal mucosa? Koplik spots - diagnostic for measles
drugs for influenza A? amantadine and rimantadine (especially prophylaxis)
drugs useful for both influenza A and B? zanamivir and oseltamivir (neuraminidase inhibitors)
virus with a bullet-shaped capsid? rabies
how does rabies travel to CNS? migrates in a retrograde fashion up axons
variant of dengue fever in Southeast Asia? hemorrhagic shock syndrome
caused by flavivirus, an arbovirus transmitted by Aedes mosquitos yellow fever
high fever, black vomit, jaundice yellow fever
councilman bodies (acidophilic inclusions) may be seen in liver with this virus yellow fever
virus causing mono with negative monospot? CMV
heterophil antibodies detected by agglutination of sheep RBCs? monospot test
tzanck test a smear of opened skin vesicle to detect multinucleated giant cells - used to assay for HSV-1, HSV-2, and VZV
Created by: Asclepius



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