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USMLE
Real Immuno 6 - Dzs by Hypersensitivity
| Question | Answer |
|---|---|
| allergic rhinitis & anaphylaxis | type I |
| hemolytic anemia | type II |
| idiopathic thrombocytopenic purpura | type II |
| erythroblastosis fetalis | type II |
| rheumatic fever | type II |
| Goodpasture's syndrome | type II |
| bullous pemphigoid | type II |
| Graves' dz | type II |
| myasthenia gravis | type II |
| SLE | type III |
| rheumatoid arthritis | type III |
| polyarteritis nodosum | type III |
| post-strep glomerulonephritis | type III |
| serum sickness | type III |
| arthus reaction | type III |
| hypersensitivity pneumonitis | type III |
| type I diabetes mellitus | type IV |
| multiple sclerosis | type IV |
| Guillain-Barre syndrome | type IV |
| Hashimoto thyroiditis | type IV |
| Graft vs Host dz | type IV |
| PPD (TB test) | type IV |
| contact dermatitis | type IV |
| IgM, IgG bind to Ag on "enemy" cell--> lysis or phagocytosis | type II (Ab-mediated) |
| Ag-Ab complexes activate complement which attracts PMNs who release dangerous substances | type III (immune complex) |
| sensitized T cells encounter Ag and release lymphokines to activate macrophages | type IV (delayed) |
| fever, urticaria, arthralgias, proteinuria, lymphadenopathy 5-10 days after Ag exposure | (serum sickness) type III |
Created by:
Asclepius
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