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The integumentary System

TermDefinition
THE INTEGUMENTARY SYSTEM DESCRIBES THE SKIN AND ITS APPENDAGES. NAMELY THE HAIR, NAILS, AND SKIN GLANDS
THE DERMAL-EPIDERMAL JUNCTION TWO PRIMARY LAYERS OF SKINS ARE JOINED
SKIN CAN BE THIS THICK (4-5MM)
SKIN CAN BE THIS THIN (1-3MM)
The Epidermal Cells TYPES Keratinocytes Melanocytes Langerhans cells
Keratinocytes Constitutes over 90% of cells present; principal structural element of the outer skin (material)
Melanocytes Pigment-producing cells ( 5% of the total); contribute to skin color; filter ultraviolet light . (color)
Langerhans dendritic (branched) antigen-presenting cells ( APCs) , they play a role in immune response (fighting immune response).
The Epidermal Cells LAYERS STRATUM GERMINATIVUM (GROWTH LAYER) STRATUM BASALE(BASE LAYER) STRATUM SPINOSUM ( SPINY LAYER)
STRATUM GERMINATIVUM (Growth Layer) describes the stratum spinosum and stratum basale together.
Stratum Basale ( Base Layer) single layer of columnar cells; only these cells undergo mitosis, then migrate through the layer until they are shed.
Stratum Spinosum (Spiny Layer) cells arranged in 8 to 10 layers with desmosomes that pull cells into spiny shapes; cells rich in RNA
Stratum granulosum ( granular layer) cells arranged in two to four layers and filled with Keratohyalin granules; contains high levels of lysosomal enzymes
Stratum lucidum ( clear layer) Cells filled with keratin precursor called eleidin; absent in the thin skin
Stratum Corneum ( horny layer) most superficial layer; dead cells filled with keratin ( barrier area).
Epidermal Growth and Repair -Turnover or regeneration time refers to time required for epidermal cells to form in the stratum basale and migrate to the skin surface ( about 35 days ) Shortened turnover time will increase the thickness of the stratum corneum and result in call
Created by: diannee
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