Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

USMLE

Biochem Nutrition

QuestionAnswer
Fat soluble vitamins A D E K
Where are fat soluble vitamins absorbed? ileum, but also depends on pancreas
B-vitamins B1=thiamine B2=riboflavin B3=niacin B5=pantothenic acid B6=pyridoxine B12=cobalamin
Vit A: Function? Deficiency? Source? Excess? aka Retinol Function: constituent of visual pigment Deficiency: night blindness, dry skin Source: leafy greens, carrots (as a precursor B-carotene) Excess: Arthralgias, fatigue, HA, sore throat, alopecia
Vit B1: Function? Deficiency? Source? aka thiamine Function: cofactor for oxidative decarboxylation (TCA cycle: a-ketoglutarate->succinyl CoA), pyruvate dehydrogenase, and HMP shunt and branched AA dehydrogenase Deficiency: early lose appetite, peripheral neuropathy, later wernicke-korsak
Vit B2: Function? Deficiency? aka riboflavin (becomes FAD or FMN) Function: cofactor for red/ox of FAHDH2 (its converterd into FAD or FMN) Deficiency: cheliosis (angular stomatitis), corneal vascularization "think 2C's"
Vit B3: Function? Deficiency? Source? aka niacin Function: converted into NAD or NADP Deficiency:Pellagras: Diarrhea, Dermatitis, Dementia Source: from diet or converted into B3 from tryptophan (with the help of B6) "think 3D's" comment: tends to only occur in places that rely corn (low
Vit B5: Function? aka pantothenoic acid Function: constituent of CoA and Fatty Acid synthase
Vit B6: Function? Deficiency? aka pyrixodine Function: cofactor for transammination, decarboxylation, heme synth, & conversion of tryptophan into Vit B3 Deficiency: Sideroblastic anemia (microcytic) convulsions, irritability, peripheral neuropathy. Def induced by INH & OCPs
Vit B12: Function? Deficiency? Source? aka cobalamin Functions: 1)converts methyl-THF into THF which is needed for nucleotide synthesis. 2) converts homocysteine into methionine 3) allows odd chain fatty acids to enter the TCA cycle (as succinyl CoA) Deficiency: megaloblastic/macrocytic an
Biotin: Function? Deficiency? Cofactor conversion of acetyl coA into fatty acid deficiency: causes dermatitis and enteritis
Vit C: Function? Deficiency? aka ascorbic acid Function: collagen synth, iron absorption, conversion of dopamine into NE Deficiency: causes Scurvy (swollen gums, bruising, anemia, poor wound healing)
Vit D: Function? Deficiency? Source? Forms? Function: increases intestinal absorption of Ca and PO4 Deficiency: causes rickets (kids), osteomalacia (adults), and hypocalcemia (tetany) Source: D2 from fortified milk D3 from sunlight conversion in skin Forms: 25-OH D3 = storage form, 1,25(OH)2 D
Vit E: Function? Deficiency? Excess? Function: antioxidant (esp protects RBCs) Deficiency: neurolodysfunction and hemolytic anemia (due to incr fragility of erythrocytes) Excess: can interfere w/Vit K
Vit K: Function? Deficiency? Source? Function: Catalyzes gamma-carboxylation of glutamic acid residues. needed for clotting factors 2, 7, 9, 10, proteins C & S Deficiency: causes clotting defects (bleeding, bruising, increased PT time) Source: Intestinal flora
Zinc: Function? Deficiency? Function: cofactor for many metalloenzymes deficiency: causes delayed wound healing, hypogonadism (less adult hair, etc), may presdispose to alcoholic cirrhosis
Kwashiorkor protein deficient "MEAL". Clinical pic is small child w/swollen belly M=malnutrition E=edema A=anemia L=liver (fatty)
Maramus Energy malnutrition (not enough calories) causes depletion of subcutaneous fat and muscle wasting. "typical starvation"
Created by: Asclepius