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EEAS Para Course

Drugs to learn for para course

QuestionAnswer
Adrenaline- Description Sympathomimetic drug (mimics the effects of transmitter substances produced by the SNS.
Amiodorone - Description Class 3 antiarrhythmic
Aspirin - Description Anti platelet, anti pyrexic, anti – inflammatory & analgesic properties
Atropine - Description Anti muscarinic agent
Benzylpenecillin - Description Broad-spectrum anti-biotic
Co-codamol - Description Analgesic
Chlorphenamine - Description Antihistamine
Clopidogrel - Description Prodrug - Antiplatelet
Diazepam - Description Benzodiazepine
Entonox - Description Inhaled analgesic agent
Furosemide - Description Diuretic
Glucagon - Description Hormone
Glucose 10% - Description
GTN - Description Prodrug - Vasodilator
Hydrocortisone - Description Glucocorticoid Steroid
Hypostop - Description
Ipratopium Bromide - Description Anticholinergic receptor
Metoclopramide - Description Antiemetic
Morphine Sulphate - Description Opioid Analgesic
Paracetamol - Description Analgesic & Anti-pyrexic
Salbutamol - Description Beta 2 Adrenoreceptor agonist
Sodium Chloride 0.9% - Description
Tranexamic Acid - Description Anti-Fibinolytic
Ace Inhibitors - Examples Perindopril, Lisinopril, Enalapril, Ramipril, Quinapril
Anti Coagulants - Examples Warfarin, Heparin
Anti Diabetic - Examples Metformin, Gliclazide
Beta Blockers - Examples Atenolol, Bisoprolol, Acebutalol, Propanolol
Calcium Chanel Blockers - Examples Verapamil, Amlodopine, Diltiazem, Felodipine, Nefedipine
Statins - Examples Simvastatin, Atorvastatin, Pravastatin
Adrenaline - Indications Cardiac Arrest Anaphylaxis Life threatening asthma with failing ventilation & continued deterioration despite nebuliser therapy
Amiodorone - Indications Cardiac arrest – Shockable rhythms after 3rd shock and additional bolus after 5th shock. Broad complex tachycardia over 150bpm if any of the following are present: <90 systolic BP, < GCS, LVF or peri-arrest. Clinical advice must be sought.
Aspirin - Indications Adults with clinical or ECG evidence suggestive of MI or ischemia
Atropine - Indications Symptomatic bradycardia in the presence of any of these adverse signs: Absolute bradycardia (<40bpm) Systolic BP below expected for age Paroxysmal ventricular arrhythmias requiring suppression Inadequate perfusion causing confusion etc
Benzylpenecillin - Indications Suspected meningococcal disease in the presence of: A non blanching rash Signs/symptoms suggestive of meningococcal septicaemia
Co-codamol - Indications Treatment of moderate to severe pain in adults and children over the age of 12
Chlorphenamine - Indications Severe anaphylactic reactions Symptomatic allergic reactions causing patient distress e.g. severe itching, hives
Clopidogrel - Indications Acute ST elevation MI (stemi)
Diazepam - Indications Fits lasting longer than 5 mins and still fitting Repeated fits–not secondary to uncorrected hypoxia or hypoglycaemia Eclamptic fits(lasting longer than 2/3 mins or if recurrent) Symptomatic cocaine toxicity(severe hypertension, chest pain or fitting)
Entonox - Indications Moderate to severe pains Labour pains
Furosemide - Indications Pulmonary oedema secondary to LVF
Glucagon - Indications Hypoglycaemia, especially in known diabetics Clinically suspected hypoglycaemia where oral glucose administration is not possible Unconscious patient where hypoglycaemia is suspected
Glucose 10% - Indications Hypoglycaemia, especially in known diabetics Clinically suspected hypoglycaemia where oral glucose administration is not possible Unconscious patient where hypoglycaemia is suspected
GTN - Indications Cardiac chest pain due to angina or MI Acute cardiogenic pulmonary oedema
Hydrocortisone - Indications Severe or life-threatening asthma, where call to hospital time is > 30 mins Anaphylaxis Adrenal crisis Patients in established adrenal crisis Steroid dependant patients who have become unwell to prevent them from having an adrenal crisis
Hypostop - Indications Hypoglycaemia, especially in known diabetics
Naloxone Hydrochloride - Description Opioid Antagonist
Ipratopium Bromide - Indications Acute severe or life threatening asthma Acute asthma unresponsive to salbutamol Exacerbation of COPD, unresponsive to salbutamol
Metoclopramide - Indications Treatment of nausea & vomiting in adults over 20 years of age Prevention & treatment of nausea & vomiting following morphine administration
Morphine Sulphate - Indications Pain associated with suspected MI (analgesic of first choice) Severe pain as a component of a balanced analgesia regimen
Naloxone Hydrochloride - Indications Opioid od producing Respiratory,CV and CNS depression Overdose of an opioid analgesic ? Reduce LOC with ? cause where opioid overdose is possible Reversal of respiratory and CNS depression in neonates following maternal opioid use during labour
Paracetamol - Indications Relief of mild to moderate pain and / or high temperature As part of a balance analgesia regimen
Salbutamol - Indications Acute asthma where normal inhaler therapy has failed to relieve symptoms Expiratory wheeze associated with allergy, anaphylaxis, smoke inhalation or lower airway cause Exacerbation of COPD SOB in patients with severe breathing difficulty due to LVF
Sodium Chloride 0.9% - Indications Adult fluid therapy Medical conditions without haemorrhage Medical conditions with haemorrhage Trauma related haemorrhage Burns Limb crush injury Child fluid therapy Medical conditions Trauma related haemorrhage Burns
Tranexamic Acid - Indications Patients with time critical injury where significant internal/external haemorrhage is suspected Injured patients fulfilling step 1 or 2 of trauma triage tool
Ace Inhibitors - Indications Hypertension & Heart failure
Anti Coagulants - Indications Prevents blood coagulation
Anti Diabetic - Indications Treatment of Diabetes
Beta Blockers - Indications Hypertension Angina Atrial Fibrillation Heart Failure
Calcium Chanel Blockers - Indications Heart Failure Coronary Heart Disease
Statins - Indications High cholesterol High risk from heart disease
Adrenaline - Actions Works via stimulation of both Alpha-1 & Beta-1 adrenergenic receptors that are found in the smooth muscle. This increases strength of ventricular contractions, heart rate & peripheral vaso-constriction. The net effect is incresed BP (mainly systolic).
Amiodorone - Actions Blocks Sodium (Na) & Potassium (K) channels within cardiac muscle, this prolongs cardiac action potential and refractory period. This results in a decreased heart rate & vascular resistance.
Aspirin - Actions Anti platelet action which reduces clot formation.
Atropine - Actions Neurotransmitter that binds to and inhibits muscarinic acetylcholine receptors that are found in the synapses and other cell membranes. Enhances AV conduction, increases heart rate & BP.
Benzylpenecillin - Actions Binds to proteins inside the cell wall & inhibits the 3rd and last stage of bacterial wall synthesis.
Co-codamol - Actions
Chlorphenamine - Actions Blocks histamine H1 receptors found in smooth muscle in both the heart and CNS. This leads to temporary relief of the negative symptoms brought on by histamine.
Clopidogrel - Actions Inhibits platelet aggregation. Prevents adenosine diphosphate from binding to its receptors on the platelets.
Diazepam - Actions CNS depressant, acts as an anti convulsant and sedative. Binds to benzodiazepine receptors and to specific subunits on GABAa receptors.
Entonox - Actions Releases biochemical substances such as endorphins and serotonin. Muscle relaxant.
Furosemide - Actions Potent diuretic, working on the loop on henle in the nephron kidney to prevent the re-absorption of water. Has a rapid onset and short duration.
Glucagon - Actions Binds to glucagon receptors and initiates a series of enzyme reactions, the end result is a release of glucose molecules into the blood. Simply glucagon acts on liver glycogen which is then converted into glucose via the release of insulin.
Glucose 10% - Actions Naturally occurring substance introduce in IV solution to increase blood glucose levels.
GTN - Actions Potent vasodilator, relaxes smooth muscle which results in coronary artery vasodilatation, < preload & < BP.
Hydrocortisone - Actions The 2 main products in inflammation prostaglandins (made at the site of tissue damage or infection, causing pain and fever) & leukotrienes , are inhibited by the action of glucocorticoids. Suppress the immune and inflammatory response.
Hypostop - Actions Naturally occurring substance introduced buccally to increase blood glucose levels.
Ipratopium Bromide - Actions Decreases the contractility of smooth muscle resulting in bronchodilation. Blocks muscarinic cholinergic receptors, muscarinic cholinergic receptor antagonist.
Metoclopramide - Actions Inhibits gastric smooth muscle relaxation. It accelerates intestinal transit & gastric emptying by preventing relaxation of gastric body. Enhances GI motility.
Morphine Sulphate - Actions Opioid receptor antagonist, mimics endorphins. Binds to MU opioid receptors in the CNS, sedative and can induce respiratory depression and hypotension.
Naloxone Hydrochloride - Actions Has a stronger affinity for bonding to opioid receptors than any opiate drug, having an antagonist effect on the receptor & cell. Reveres the effect of opioid drugs.
Paracetamol - Actions Interrupts prostaglandin synthesis which regulates the contraction & relaxation of smooth muscle to reduce inflammatory response, has analgesic property, and reduces pyrexia by inducing peripheral vasodilatation & sweating.
Salbutamol - Actions Selective beta 2 adrenoreceptor stimulant, relaxes smooth muscle in the small and medium airways
Sodium Chloride 0.9% - Actions Increases vascular fluid volume which consequently raises cardiac output & improves perfusion
Tranexamic Acid - Actions An anti-fibinolytic drug that helps to prevent the breakdown of a formed blood clot.
Ace Inhibitors - Actions Stop the body from creating Angiotensin II. They do this by blocking a chemical called Angiotensin converting enzyme, this essentially relaxes blood vessels and helps reduce the amount of water re-absorbed by the kidneys lowering blood pressure.
Anti Coagulants - Actions Blocks the effects of vitamin K which is needed to make some of the bloods clotting factors. Blocking vitamin K prevents blood clots forming so easily by increasing the time it takes to make fibrin.
Anti Diabetic - Actions Acts by increasing the sensitivity of liver, muscle, fat and other tissues to the uptake and effects of insulin. These actions lower the level of sugar within the blood
Beta Blockers - Actions Primarily blocks b1 & b2 receptors and thereby the effects of Noradrenaline and Adrenaline. By blocking these effects Beta Blockers reduce BP by dilating blood vessels. They may also reduce air passage by stimulating the muscles that surround air passages
Calcium Chanel Blockers - Actions Prevent calcium from entering of the heart and blood vessel walls, this prevents muscle contraction and reduces BP.
Statins - Actions Cells in the body produce cholesterol and require it to work correctly, statins work by reducing the amount of cholesterol produced by the cells. This forces them to get their supply by removing it from the bloodstream.
Created by: 833227113