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Adult Health Nursing

Ch 4 pharm MEL

QuestionAnswerAnswerAnswer Answer Answer
Vitamin D - dihydroxy 6 - 52
Alkaline phosphatase 30 - 120
Erythrocyte sedimentation rate (ESR) M = up to 15 W = up to 20
Lupus Erythematous (LE) No LE cells seen
Rheumatoid factor (RF) <60 units per ML
Uric acid (blood) M = 2.1 - 8.5 W = 2.0 - 6.6
Salicylates Aspirin, salicylate Anti-inflammatory, analgesic, antipyretic, act by inhibiting synthesis of prostaglandins Prolonged bleeding, Tinnitus, dizziness with repeated large doses, exacerbation of asthma, G.I. irritation(dyspepsia, nausea, ulcer, hemorrhage) RA
NSAIDs Indomethacin/Indocin Analgesic, anti-inflammatory Headache, vertigo, insomnia; confusion, G.I. irritation, can decrease the effects of ACE inhibitors RA
NSAIDs Ibuprofen/Motrin: Advil Analgesic, anti-inflammatory Headache, vertigo, insomnia; confusion, less irritating to G.I. tract, fluid retention, can cause hypertension RA
NSAIDs Naproxen/naprosyn Analgesic, anti-inflammatory Same as ibuprofen, also causes drowsiness RA
COX-2 inhibitors Celebrex/celecoxib Analgesic, anti-inflammatory Mild to moderate indigestion, risk of G.I. bleeding, diarrhea, abdominal pain monitor for MI or stroke RA
Potent anti-inflammatory agents Adrenocortical steroids/prednisone Interferes with bodies normal inflammatory responses Increases BP, fluid retention, osteoporosis, adrenal insufficiency, moon face, increased blood sugar in diabetics, slow wound healing, and Na retention, K + depletion,hypertension RA
Antineoplastic Trexall: Folex: Rheumatrex/methotrexate Alters the way the body uses fully acid, which is necessary for cell growth; decreases inflammation Upset stomach, N&V, anorexia, diarrhea, sore mouth; headache, blurred vision, dizziness RA
DMARDs= Disease modifying anti-rheumatoid drugs Enbrel/Etanercept subQ Blocks the normal in inflammatory immune responses seen in RA; binds TNF: which is involved in immune and inflammatory reactions Pain at injection site, upper respiratory tract infections and sinusitis; in severe cases of tuberculosis possible RA
DMARDs= disease modifying anti-rheumatoid drugs Infliximab/Remicade IV Anti-body that bind specifically to pro-inflammatory enzymes that are produced by the synovial cells Upper respiratory tract infections, headache, nausea, sinusitis, rash, cost RA
DMARDs = disease modifying anti-rheumatoid drugs Humira/Adalimumab Reduces infiltration of inflammatory cells can increased risk of infection, headaches and rash; neutropenia; injection site reaction Assess for signs of infection before injection, do not give to patients with active injections, monitor new infections closely RA
Osteoporosis Biophosphates Fosamax, Alendronate Slow bone loss and increase bone density Difficulty in swallowing, chest pain, severe or recurring heartburn Pill, sitting upright, @least 30 minutes before other meds
Calcium 9.0 - 10.5
Phosphorus 2.5 - 4.5
Created by: diamondgirljaz