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Lympatic & Hematopoi

Med Surg

Hematopoesis def manufacture and development of blood cells
Leukocytosis vs leukopenia leukocytosis - to many WBC; leukopenia - definency of WBC
Name the 4 blood types. Which is universal donor and which is universal recipient? A,B,AB,O; O - universal donor; AB - universal recipient b/c A&B antigens are present and wont fight it
Name components of lymphatic system (4) thymus, spleen, lymph nodes (glandular tissue), lymph fluid - similar to plasma in composition
What is the stilling test used for? dx pernicious anemia, macrolytic anemia & malabsorption syndromes
Anemia def deficiency of erthyrocytes & hemoglobin which reduces amt of oxygen carried to cells
Causes of anemia (3) blood loss, inadequate erythrocyte production, destruction of normally formed RBC
Hypovolemic anemia d/t blood loss' compromised cellular function. hemoglobin saturation >90%
Iron definency anemia insufficient iron for hemoglobin production; reduced energy, rapid HR
Sickle Cell Anemia hemoglobin S; inadequate O2 in blood hereditary, hypoxia, hemolytic anemia
Sickle cell crisis vascular occulation that occurs under hypoxic conditions
Hemolytic Anemia chronic premature and erythrocyte destruction - obstruction of RBC
Thalassemias Types Alpha - asymptomatic; Beta-Cooleys anemia - sx of severe anemia; bronze skin - both hereditary
Pernicious Anemia lack of intrinsic factor necessary for absorption of vitamin B12; degenerative changes in nervous system
Folic Acid Deficency Anemia immature erythrocytes d/t vitamin B9 deficency
Erythrocytosis: Polycthemia vera rapid proliferation of blood cells produced by the bone marrow - increase in circulating proliferites; life span shorter; increase in uric acid levels
Leukocytosis:Leukemia proliferation of leukocytes - usually immature forms; precipitating factors; genetic correlation - increase in WBC; hereditary, viruses, radiation; infections increase; anemia
Multiple myeloma malignancy involving plasma cells, osteoclasts break down cells, increase blood calcium; pathologic fracture; associated with aging - NKC; poor prognosis
Agranulocytosis Drug toxicity, decrease in production of granulocytes and opposed to leukopenia - 6months-1yr
Pancytopenia - Aplastic anemia autoimmune; exposure to toxic chemicals, radiation, and drug therapy - all marrow produced blood cells are reduced
Coagulopathies - thromboctyopenia platelets; decreased manufacture or increased destruction
Coagulopathies - hemophilia clotting factors inherited - mother to son
Lymphedema impaired lymph circulation - primary and secondary. women more than men; repeated phlebitis
lymphangitis/lymphadenitis strepococcal microorganisms
infectous mononucleosis epstein-bar virus; direct contact-secretions
lymphoma's - hodgkins disease reed-sternberg cells. malignancy that produces enlargement of lymphoid tissue, spleen & liver w/invasion of other tissues
non-hodgkins lymphomas genetic link, environmental trigger, aggressive
Created by: breinard