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Renal
Renal System Physiology, Calculations
Question | Answer |
---|---|
ECF | Increase in NaCL decrease K+ |
ICF | Decrease in NaCl Increase K+ |
plasma volume measured by | radiolableled albumin |
ECV measured | inulin |
Cx>GFR | net tubular secretion |
Cx<GFR | net tubular reabsorption |
Cx=GFR | there is no net secretion or reabsorption |
PGE on afferent arterioles | dilate arterioles ↑ RPF, ↑GFR, so FF is constant |
Angiotensin II on efferent arterioles | constriction ↑ GFR so ↑FF, ↓ RPF |
Afferent arteriole constriction | ↓RPF ↓GFR NC in FF |
Efferent arteriole constriction | ↑ GFR so ↑FF, ↓ RPF |
↑ plasma protein concentration | NC RPF ↓ GFR ↓FF |
↓ plasma protein concentration | NC RPF ↑ GFR ↑FF |
constriction on ureter | NC RPF ↓ GFR ↓FF |
what blocks efferent arterioles | ACE inhibitors |
What blocks afferent arterioles | NSAIDS |
clinical measure to estimate GFR | Creatinine clearance |
which terminal vessels carry blood toward the glomerulus | Afferent arterioles |
site reabsorption of all glucose and amino acids, and the majority of bicarbonate, sodium and water | PCT |
site of active reabsorption K+, Na+, Cl- | Thick ALH` |
site of 50% of urea absorption | PCT [passively] |
Site of active reabsorption of Na+, Cl- | Early distal convoluted tubule |
Site of action of thiazide diuretics | DCT |
Site of action of K+ sparing diuretics | collecting tubules |
section that is impermeable to water | thick ascending loop of henle |
site where ammonia is excreted to act as a buffer for secreted H+ ions | PCT |
Portion of the nephron which is impermeable to Na+ and passively reabsorbs water | Thin descending loop of Henle |
Aldosterone sensitive site where Na+ is exchanged for K+ and H+ | collecting tubules |
Site of active Ca2+ reabsorption that is controlled by PTH | early DCT |
Site of action of loop diuretics | Thick ascending loop of Henle |
Section where reabsorption of water is regulated by vasopressin | Collecting tubules |
Site of action of carbonic anhydrase inhibitors | PCT |
section which containes principle cells and intercalated cells | Collecting tubules |
Site of 85% of all phosphate reabsorption [via cotransport] | PCT |
RPF can be estimated | PAH |
urine is more hypertonic | Thin descending loop of Henle |
Makes urine more hypotonic | Early DCT, Thick Ascending Loop of henle |
ANP action | [secrete atrial pressure]decrease Na+, increase GFR |
PTH action | secreted in response to decrease plasma [Ca2+] increase Ca2+ reabsorption DCT decrease in PO reabsorption PCT |
Aldosterone | secreted in response to decrease BV and increase plasma K+ causes Increase in Na+ reabsorption and K+ secretion |
Vasopressin ADH | secreted in response to increase plasma osmolarity and decrease blood volume |
AT II | increase intravascular volume --> in Na+ and HCO3- reabsorption |