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Renal
Renal System Physiology, Calculations
| Question | Answer |
|---|---|
| ECF | Increase in NaCL decrease K+ |
| ICF | Decrease in NaCl Increase K+ |
| plasma volume measured by | radiolableled albumin |
| ECV measured | inulin |
| Cx>GFR | net tubular secretion |
| Cx<GFR | net tubular reabsorption |
| Cx=GFR | there is no net secretion or reabsorption |
| PGE on afferent arterioles | dilate arterioles ↑ RPF, ↑GFR, so FF is constant |
| Angiotensin II on efferent arterioles | constriction ↑ GFR so ↑FF, ↓ RPF |
| Afferent arteriole constriction | ↓RPF ↓GFR NC in FF |
| Efferent arteriole constriction | ↑ GFR so ↑FF, ↓ RPF |
| ↑ plasma protein concentration | NC RPF ↓ GFR ↓FF |
| ↓ plasma protein concentration | NC RPF ↑ GFR ↑FF |
| constriction on ureter | NC RPF ↓ GFR ↓FF |
| what blocks efferent arterioles | ACE inhibitors |
| What blocks afferent arterioles | NSAIDS |
| clinical measure to estimate GFR | Creatinine clearance |
| which terminal vessels carry blood toward the glomerulus | Afferent arterioles |
| site reabsorption of all glucose and amino acids, and the majority of bicarbonate, sodium and water | PCT |
| site of active reabsorption K+, Na+, Cl- | Thick ALH` |
| site of 50% of urea absorption | PCT [passively] |
| Site of active reabsorption of Na+, Cl- | Early distal convoluted tubule |
| Site of action of thiazide diuretics | DCT |
| Site of action of K+ sparing diuretics | collecting tubules |
| section that is impermeable to water | thick ascending loop of henle |
| site where ammonia is excreted to act as a buffer for secreted H+ ions | PCT |
| Portion of the nephron which is impermeable to Na+ and passively reabsorbs water | Thin descending loop of Henle |
| Aldosterone sensitive site where Na+ is exchanged for K+ and H+ | collecting tubules |
| Site of active Ca2+ reabsorption that is controlled by PTH | early DCT |
| Site of action of loop diuretics | Thick ascending loop of Henle |
| Section where reabsorption of water is regulated by vasopressin | Collecting tubules |
| Site of action of carbonic anhydrase inhibitors | PCT |
| section which containes principle cells and intercalated cells | Collecting tubules |
| Site of 85% of all phosphate reabsorption [via cotransport] | PCT |
| RPF can be estimated | PAH |
| urine is more hypertonic | Thin descending loop of Henle |
| Makes urine more hypotonic | Early DCT, Thick Ascending Loop of henle |
| ANP action | [secrete atrial pressure]decrease Na+, increase GFR |
| PTH action | secreted in response to decrease plasma [Ca2+] increase Ca2+ reabsorption DCT decrease in PO reabsorption PCT |
| Aldosterone | secreted in response to decrease BV and increase plasma K+ causes Increase in Na+ reabsorption and K+ secretion |
| Vasopressin ADH | secreted in response to increase plasma osmolarity and decrease blood volume |
| AT II | increase intravascular volume --> in Na+ and HCO3- reabsorption |
Created by:
Roshani
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