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Musculoskeletal
Musculoskeletal Diseases and Bone Cancers
| Question | Answer |
|---|---|
| Most common bone tumor | Metastatic tumors to bone [Prostate, Breast and Lung cancers] |
| Most common primary bone tumor | Multiple Myeloma |
| Most common Benign tumor of the bone | Osteochondroma or exotosis |
| Second Most common primary tumor of Bone | Osteosarcoma [Malignant] |
| Benign sesile tumor attached to the bone surface, usally affecting skull and facial bone | Osteoma |
| What is an Osteoma associated with | Garderners syndrome [FAP] New piece of bone grows on another piece of bone |
| Benign tumor <2cm that is painful at night due to excess PGE2, and relieved with aspirin and common in males <25 y/0 | Osteoid Osteoma |
| Malignant tumor typically occuring in the metaphysis regio prior to epiphyseal closure in patients <25 y/0 | Osteosarcoma |
| Mushroom shape [cartilaginous cap] laterally protruding tumor that may result from lateral displacement of growth plate | Osteochondroma or exotosis |
| Benign tumor composed primary of mature hyaline cartilage | chondroma |
| Benign tumor composed of fibrous trabeculae of womven bone resembling chinese letters | fibrous dysplasia |
| nodule of hyaline cartilage encased in reactive bone | enchondroma |
| malignant, painful small round blue cell tumor of childhood occuring typically in the appendicular skeleton [may affect ribs] | Ewings Sarcoma/Primitive neuroectodermal tumor [PNET] |
| Benign tumor composed of multinucleated giant cells within a fibrous stroma occuring in the epiphyses of long bones | Giant cell tumor of the bone/ Osteoclastoma |
| Lace like pattern of bone produced by tumor cells | Osteosarcoma |
| Homer Wright pseudorosettes | Ewings Sarcoma/PNET |
| Soap bubble appearance on XR | Giant cell tumor of bone |
| Malignant tumor of cartilage found in the central skeleton | Chondrosarcoma |
| Benign but painful bone tumor that appears as a radiolucent nidus surrounded by dense bone | Osteoid osteoma or osteoblastoma [larger and found in vertebral column] |
| Codmans triangle forms as a tumor causes periosteal elevation | Osteosarcoma |
| Triad of polysostotic fibrous dysplasia, cafe' au lait spots, precocious puberty, and other endocrine disorders [pediatric disease] | McCune-Albright syndrome |
| pediatric disease: triad of skull lesions, diabetes, inspidus, and exopthalmos | Hand-Schuller-Christina disease or histocytosisX |