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Musculoskeletal Diseases and Bone Cancers

Most common bone tumor Metastatic tumors to bone [Prostate, Breast and Lung cancers]
Most common primary bone tumor Multiple Myeloma
Most common Benign tumor of the bone Osteochondroma or exotosis
Second Most common primary tumor of Bone Osteosarcoma [Malignant]
Benign sesile tumor attached to the bone surface, usally affecting skull and facial bone Osteoma
What is an Osteoma associated with Garderners syndrome [FAP] New piece of bone grows on another piece of bone
Benign tumor <2cm that is painful at night due to excess PGE2, and relieved with aspirin and common in males <25 y/0 Osteoid Osteoma
Malignant tumor typically occuring in the metaphysis regio prior to epiphyseal closure in patients <25 y/0 Osteosarcoma
Mushroom shape [cartilaginous cap] laterally protruding tumor that may result from lateral displacement of growth plate Osteochondroma or exotosis
Benign tumor composed primary of mature hyaline cartilage chondroma
Benign tumor composed of fibrous trabeculae of womven bone resembling chinese letters fibrous dysplasia
nodule of hyaline cartilage encased in reactive bone enchondroma
malignant, painful small round blue cell tumor of childhood occuring typically in the appendicular skeleton [may affect ribs] Ewings Sarcoma/Primitive neuroectodermal tumor [PNET]
Benign tumor composed of multinucleated giant cells within a fibrous stroma occuring in the epiphyses of long bones Giant cell tumor of the bone/ Osteoclastoma
Lace like pattern of bone produced by tumor cells Osteosarcoma
Homer Wright pseudorosettes Ewings Sarcoma/PNET
Soap bubble appearance on XR Giant cell tumor of bone
Malignant tumor of cartilage found in the central skeleton Chondrosarcoma
Benign but painful bone tumor that appears as a radiolucent nidus surrounded by dense bone Osteoid osteoma or osteoblastoma [larger and found in vertebral column]
Codmans triangle forms as a tumor causes periosteal elevation Osteosarcoma
Triad of polysostotic fibrous dysplasia, cafe' au lait spots, precocious puberty, and other endocrine disorders [pediatric disease] McCune-Albright syndrome
pediatric disease: triad of skull lesions, diabetes, inspidus, and exopthalmos Hand-Schuller-Christina disease or histocytosisX
Created by: Roshani