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Microbiology 3
Immunology
| Question | Answer |
|---|---|
| Natural/innate immunolgy | Physical barriers, antimicrobial chemicals, phagocytic body cells, natural killer cells |
| Humoral acquired immunity | Anitbody synthesis, resistance to extracellular bacteria, neutralization of viruses, protection of fetus/newborn |
| Cell-mediated acquired immunity | Killer cells, resistance to parasites in cells, regulation of antibody synthesis, control of cancer cells, graft rejection |
| First line of body's defenses | Intact skin, mucous membranes and secretions, normal microbacteria |
| Second line of body's defenses | Phagocytic white blood cells, inflammation, fever, antimicrobial sustances |
| Third line of body's defenses | Specialized lympocytes, B and T cells |
| Phagocytic cells | Generally leukocytes, also called white blood cells |
| Interferon | General antivirus |
| B-cells | Stem cells differentiated in the bone marrow, responsible for antibody production |
| T-cells | Stem cells differentiated in the thymus, responsible for cell-mediated immunity |
| Memory B-cells | B-cells that stay in the bloodstream after an infection to provide protection for future infections |
| Plasma B-cells | B-cells produced in the case of an infection to fight off the foreign cells |
| Macrophage | Possesses multiple structures called psuedopodes |
| Stage 1 of inflammation | Chemotactic response |
| Stage 2 of inflammation | Blood clot forms |
| Stage 3 of inflammation | Abscess starts to form |
| Stage 4 of inflammation | Margination: phagocytes stick to endothelium |
| Stage 5 of inflammation | Emigration: phagocytes squeeze between endothelial cells |
| Stage 6 of inflammation | Phagocytosis of invading bacteria |
| Chills | Systemic response to internal body temperature going up and external temperature going down |
| Antigenic substances | Elict immune response |
| Antibodies | Proteins that can form structures to recognize determinants |
| Haptens | Can be determinants, but cannot elict immune response, formed from two parts |
| Serum proteins | Proteins in blood |
| Immunoglobulin M | First immunoglobulin to appear after immunization |
| Immunoglobulin A | Primarily found in secretions and extracellular fluids |
| Immunoglobulin D | Major circulating antibody |
| Immunoglobulin E | Major enzyme in allergic reactions |
| Immunoglobulin G | Major serum immunoglobulin |
| Attenuated virus | Living, but weakened virus used in vaccines |
| Inactivated virus | Killed virus used in vaccines |
| Toxoids | Inactivated toxin used in vaccines |
| Clonal memory | anamastic response, remembering antigens to fight them better next time |
| Vaccine | Promotes immune response, developed in 1798 by Ed Jenner |