Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Pharm - Immunology

Immunology Pharmacology from First Aid 2013

Cyclosporine: MOA, Use, Tox MOA: bind to cyclophilins and inactivates calcineurin, inhibiting IL-2/T-Cell diff Use: prevent organ rejection after Tx Tox: nephrotox, HTN, hyper glyc/lipidemia, tremor, gingival hyperplasia, hirsutism
Tacrolimus (FK-506): MOA, Use, Tox MOA: binds to FK and inactivates calcineurin, inhibiting IL-2/T-Cell diff Use: potent immunosuppressor, organ Tx Tox: like cyclosporine; no gingiva, hirsutism
What is sirolimus? What are its uses and toxicities? Rapamycin, mTOR inhibitor Use: kidney Tx, with others Tox: hyperlipidemia, other cytopenias
Azathioprine: MOA, Use, Tox MOA: 6-MP, toxic to proliferating lymphocytes Use: kidney Tx, A/I glomerulonephritis or AIHA Tox: BM suppression, toxic with allopurinol
Muromonab-CD3 (OKT3): MOA, Use, Tox MOA: Ab vs. CD3 on T-Cells Use: after kidney Tx Tox: cytokine release syndrome, H-S rxn
Infliximab,: MOA and use MOA: anti TNFa Use: Anti-PAIR (HLA-B27) diseases
What is adalimumab? It's an anti-TNFa ab like infliximab.
When do you use alpha interferon? Hep B and C, Kaposi's sarcoma, leukemias, malignant melanoma
When do you use beta interferon? Multiple sclerosis
When do you use gamma interferon? Chronic granulomatous disease
Created by: wmwebb89