Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Pharm - Pulmonary

Pulmonary Pharmacology from First Aid 2013

Antihistamines block which receptor? H1
First generation H1 blockers treat what? Name some. Allergy, motion sickness, sleep aid. They are more sedating because they cross into the CNS. Diphenhydramine, dimenhydrinate, chlorpheniramine.
Second generation H1 blockers treat what? Name some. Allergy only. They're far less sedating. Loratadine, fexofenadine, desloratadine, ceterizine (usually end in "-adine")
What is the classic beta-2 agonist used in acute asthma? Albuterol
What are salmeterol, formoterol? What are their side effects? Long-acting beta-2 agonists used in the prophylactic treatment of asthma. SFX: tremor, arrhythmia
Theophylline: MOA, Use, Tox MOA: inhibits PDE, increasing cAMP Use: bronchodilation in asthma Tox: CYP450, nephro- and cardiotoxicity. Blocks action of adenosine***
Ipratropium: MOA, Use, Tox MOA: blocks muscarinic receptors Use: prevents bronchoconstriction in asthma Also used in COPD.
How are corticosteroids used in asthma? "-asones" inhibit the synthesis of all cytokines and inactivate NF-kB, the TF that induces TNFa. First line therapy for chronic asthma prevention.
How are anti-leukotrienes used in asthma treatment? They block leukotriene receptors or LOX acitivity and so are especially good for aspirin-induced asthma. Montelukast, zafirlukast - block receptors Zileuton - inhibit LOX
Omalizumab: MOA, Use, Tox Anti-IgE antibody, used in asthma resistant to other treatment.
Which asthma therapies target the early response (symptoms), and which target the late response (inflammation)? Early: beta-agonists, theophylline, anti-muscarinics Late: steroids, anti-leukotrienes
What are cromolyn drugs? They block mast cell degranulation. They used to be common in asthma treatment but have since been replaced by anti-leukotrienes.
Guaifenesin: MOA, Use Expectorant that thins mucus secretions but does not suppress the cough reflex.
What is N-acetylcysteine's use in the context of the respiratory system? It is a mucolytic that can loosen mucus plugs in CF patients.
Bosentan: MOA, Use MOA: Competitively antagonizes endothelin-1, decreasing PVR. Use: Treats pulmonary artery HTN.
Dextromethorphan: MOA, Use, Tox MOA: as an anti-tussive, stimulates NMDA glutamate receptors. Tox: as a codeine analog, has mild opioid effects; Rx O/D with naloxone
Pseudoephedrine, phenylephrine: MOA, Use, Tox MOA: sympathetic a-agonists, decongestant Use: reduce nasal hyperemia, congestion Tox: HTN, and a stimulant (weight loss)
Methacholine: MOA, Use MOA: muscarinic receptor agonist Use: used in asthma challenge testing
Created by: wmwebb89



Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards