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Biology Chapter 8
DNA: the genetic material
| Term | Definition |
|---|---|
| DNA | Deoxyribonucleic Acid |
| Virulent | Able to cause disease |
| Bacteriophage | A virus that infects bacteria |
| Nucleotides | Subunits of molecules |
| Deoxyribose | 5 carbon sugar in nucleotide |
| Purines | Large, double ringed molecules; adenine and guanine |
| Pyrimidines | Single ringed molecules; thymine and cytosine |
| Adenine + | Thymine |
| Guanine + | Cytosine |
| Double helix | Spiral staircase of two stands if nucleotides twisting around the center axis |
| Replication | The process of synthesizing a new strand of DNA |
| Helicases | Enzyme that opens up the double helix by breaking the hydrogen bins that link the complementary bases |
| Replication fork | Point at which the double helix separates |
| DNA polymerase | Enzymes that move down the DNA strands adding nucleotides to the exposed bases |
| Introns | Noncoding sequences; intervening sequences |
| Exons | Nucleotide segments that code for amino acids |
| Multigene families | Clusters of almost identical sequences |
| Transposons | Genes that have the ability to move from one chromosomal inaction to another |
| Griffith | Transformation experiments; mice |
| Oswald Avery | Announced genetic material was DNA |
| Hersey and chase | Clear and indisputable evidence that genetically material was DNA |
| Chargaff | Base-pairing rules |
| Maurice Wilkins and Rosalind Franklin | X-ray diffraction of the structure of DNA |
| Watson and crick | First model of structure of DNA |
| Barbara McClintock | Discovered transposons |
| p53 | Protein 53; gene that suppresses tumors |