click below
click below
Normal Size Small Size show me how
Nur-341
Exam #4 - Substance Abuse Disorders
| Term | Definition |
|---|---|
| What three ways do drugs increase neurotransmitter concentrations? | Lock onto receptors, lock onto neuron or prevent reuptake |
| What neurotransmitters are involved in addiction? | Dopamine, serotonin, acetylcholine, GABA, and glutamate |
| What are the two types of substance related disorders in the DSM-V? | Substance use disorders and substance induced disorders |
| What does it mean to have a dual diagnosis? | Substance abuse and psychiatric disorder |
| What does CAGE stand for? | Cut-down, annoyed, guilty, eye-opener |
| What is AUDIT used for? | A screening tool for alcohol use; a series of 10 questions scored 0-4; a score higher than 8 for men indicates a problem; a score higher than 7 indicates a problem for women |
| Name three CNS depressants? | Alcohol, barbiturates and benzodiazepines |
| What is the mechanism of action of alcohol? | Sedative affect by increasing GABA and decreasing glutamate |
| When does alcohol withdrawal begin? | Starts at 4-12 hours after last drink |
| What happens to vital signs with alcohol withdrawal? | Everything increases: HR, RR, BP, temperature |
| What older medication is used to promote abstinence from alcohol? | Disulfiram (Antabuse) |
| What opiate antagonist is used to promote abstinence from alcohol? | Naltrexone (Revia, Vivitrol) |
| What medication diminishes craving for alcohol by blocking receptors? | Trexone |
| What GABA agonist is used to promote abstinence from alcohol by exerting a calming, relaxing effect? | Acamprosate (Campral) |
| What effect do barbiturates exert? | Excessive drowsiness |
| Name two examples of barbiturates | Seconal (secobarbital) and Phenobarbital |
| Which class of CNS depressants are long acting and less harmful in overdose? | Benzodiazepines |
| Name four examples of benzodiazepines | Lorazepam (Ativan), Alprazolam (Xanax), Diazepam (Valium), Clonazepam (Klonopin) |
| Name the antidote for benzodiazepine respiratory depression | Flumazenil (Romazicon) |
| Name three drugs that are considered CNS stimulants. | Amphetamines, cocaine, and caffeine |
| What mode of action do amphetamines have? | Increase norepinephrine, dopamine and serotonin |
| Name four examples of amphetamines | Methamphetamine, dextroamphetamine, benzphetamine, ecstasy |
| What drug produces a high 12X that of sex? | Amphetamines |
| What is the most commonly used drug in the world? | Caffeine |
| Withdrawal from these two CNS stimulants includes intense cravings | Amphetamines and cocaine |
| What is the mode of action of cocaine? | Activates dopamine transmission in the limbic system |
| What can an overdose of opiates lead to? | Death by respiratory depression |
| What is the antidote for an opiate overdose? | Narcan |
| Withdrawal symptoms of this drug resembles the flu | Opiates |
| What antihypertensive medication is used to promote withdrawal/abstinence from opiates? | Clonidine (Catapres) |
| What controversial medication is used to promote withdrawal from opiates? | Methadone (Dolophine) |
| What partial opioid antagonist is used to promote withdrawal/abstinence from opiates and is taken sublingually? | Buprenorphine (Subutex, Suboxone) |
| What is the most common illicit drug in the U.S? | Cannabis (Marijuana) |
| There is a high rate of use of this illicit drug in people who present with a first psychosis | Marijuana |
| This class of drugs induces a psychotic state known as perceptual distortions | Hallucinogens |
| Name three examples of hallucinogens | LSD, Mescaline, PCP |
| Use of this hallucinogen can produce "bad trips" | LSD |
| Use of this hallucinogen can lead to desensitization and person can be hurt and not have a sense of it | PCP |
| This disorder describes intermittent flashbacks that occur for years post-use | Hallucinogen Persisting Perception Disorder |
| This drug acts as both a stimulant and a depressant | Nicotine |
| This drug mimics acetylcholine in the brain | Nicotine |
| This drug increases and prolongs the action of dopamine | Nicotine |
| This smoking-cessation medication is begun 2 weeks before the person actually quits smoking | Buproprion (Zyban) = Wellbutrin |
| This smoking-cessation medication is more effective than Zyban but has some serious psychiatric side effects | Varenicline (Chantix) |
| A genetic mutation of this gene can leave some people with a tendency towards anxiety, anger, and low self-esteem | DRD2 Gene |
| What does CIWA-Ar stand for? | Clinical Institute Withdrawal Assessment for Alcohol Revised |
| How is the CIWA-Ar used? | 10 withdrawal symptoms are rated on a scale of 0-7; if the total score is > 10, then benzodiazepines are needed for withdrawal (calms and prevents seizures) |
| What does IOP stand for? | Intensive Outpatient Program |
| At what stage of the transtheoretical model of change is a person ready to accept suggestions and strategies to change their drug use? | Preparation stage |
| What is the most common treatment for addiction? | Self-help groups |