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MICRO review
| Question | Answer |
|---|---|
| unique to the fungi | Ergosterol |
| most common flora organism on the skin | S. epidermidis |
| protect bacteria against phagocytosis | protein A, capsules, and some pili |
| pathogenicity factor produced by all gram-negative prokaryotes | Lipid A is the toxic component of endotoxin or lipopolysaccharide, which makes up the outer membrane |
| possessed by all gram-positives | Teichoic acid |
| Endospores are produced by two genera of gram-positive bacteria, | Clostridium and Bacillus |
| Peptidoglycan is found in the cell wall of all prokaryotes except | Mycoplasma; contains sterols |
| Painless, indurated genital ulcers during primary syphilis caused by | Treponema pallidum |
| Used to visualize treponemes in fluid from chancre | Dark-field microscopy |
| Serologic testing for Treponema pallidum NON-SPECIFIC | VDRL/RPR |
| CONFIRM diagnosis of syphilis with SPECIFIC test | FTA-ABS |
| Diagnose 3º syphilis; neurosyphilis | test spinal fluid with VDRL or RPR |
| most important test to distinguish between the gram-positive cocci of the genera Streptococcus and Staphylococcus. | catalase test |
| is used to distinguish between Streptococcus pyogenes and S. agalactiae | CAMP test |
| is used to identify Staphylococcus aureus specifically | Coagulase test |
| A maculopapular rash begins on the ankles and wrists and spreads to his trunk | Rocky Mountain spotted fever, which is caused by Rickettsia rickettsii |
| intracellular pathogen because it cannot make enough ATP for independent existence. | Rickettsia rickettsii |
| only prokaryotes that possess sterols in their membranes | Mycoplasma and Ureaplasma |
| lack muramic acid in their cell walls | Chlamydia |
| specific test for the diagnosis of syphilis | fluorescent treponemal antibody-absorption test (FTA-ABS) |
| N. gonorrhoeae and N. meningitidis are distinguished from one another by the fact | N. meningitidis ferments maltose and has a capsule |
| Atypical pneumonia | Mycoplasma, Legionella, Chlamydia |
| Atypical pneumonia in an elderly | Mycoplasma |
| struvite stones or staghorn renal calcul, possible following UTI by organisms that are urease producers, change urinary pH | Proteus spp. or Ureaplasma urealyticum. |
| Organisms that DONT Gram stain well | Treponema, Mycobacteria, Mycoplasma, Legionella, Rickettsia, Chlamydia |
| high lipid content in cell wall detected by carbolfuchsin in acid-fast stain (Ziehl-Neelsen) | Nocardia, Mycobacterium |
| Mycobacterium tuberculosis pathogenicity | Cord factor+ sulfatides= inhibit phagosome-lysosome fusion |
| more common bacterial cause of diarrhea in the United States | Campylobacter jejuni |
| All DNA viruses replicate in the nucleus EXCEPT | Poxvirus |
| All RNA viruses replicate in the cytoplasm EXCEPT | Influenza, Retrovirus |
| Only viruses insensitive to alcohol | naked capsid |
| Interferon-alpha has been used with success in the treatment of these diseases | Hairy B cell leukemia, chronic hepatitis B and C, Kaposi sarcoma, condyloma acuminatum, renal cell carcinoma, malignant melanoma |
| Interferon-beta has been shown to increase the length of remissions | Multiple sclerosis |
| Interferon-gamma has been used to increase phagocytic cell function in | Chronic granulomatous disease |
| How do retroviruses make their messenger RNA | By transcription from proviral DNA |
| This is the only family of single-stranded DNA viruses. | Parvovirus |
| Host is one in which the virus is not able to produce virions, but instead malignant transformation occurs | Nonpermissive |
| Host permits viral replication and either lives or dies as a result of the number of cells killed. | Permissive |
| only family of viruses that captures their envelope from the nuclear membrane of the infected cell. | Herpesviruses |
| Most of the members of the family virus are agents of aseptic meningitis. | Picornaviridae (poliovirus, enterovirus, coxsackie virus) |
| molecule that binds to CD4 and gives the HIV virus its tropism | gp120 |
| gp41 | fusion and entry |
| gag (p24) | capsid protein |