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College Biology1

Biology - Ch15

TermDefinition
chromosome theory of inheritance A basic principle in biology stating that genes are located at specific positions (loci) on chromosomes and that the behavior of chromosomes during meiosis that accounts for inheritance patterns.
wild type The phenotype most commonly observed in natural populations; also refers to the individual with that phenotype
linked gene Genes located close enough together on a chromosome that they tend to be inherited together
x-linked genes A gene located on the X chromosome; such genes show a distinctive pattern of inheritance
duchenne muscular dystrophy A human genetic disease caused by a sex linked recessive allele; characterized by progressive weakening and loss of muscular tissue
hemophilia A human genetic disease caused by a sex linked recessive allele resulting in the absence of one or more blood clotting proteins; characterized by excessive following injury.
barr body a dense object lying along the inside of the nuclear envelope in cells of female mammals, representing a highly condensed, inactivated X chromosome.
genetic recombination General term for the production of offspring with combinations of traits that differ from those found in either parents
parental types an offspring with a phenotype that matches one of the true breeding parental(P generation) phenotypes; also refers to phenotype itself
recombinant types (recombinants) an offspring who’s phenotype differs from that of the true breeding p generation parents; also refers to phenotype itself
crossing over the reciprocal exchange of genetic material between non sister chromatids during prophase 1 of meiosis
genetic map An ordered list of genetic loci (genes or other genetic markers) along the chromosome
linkage map A genetic map based on the frequencies of recombinations between markers during crossing over of homologous chromosomes
map units A unit of measurement of the distance between genes. One map unit is equivalent to a 1% recombination frequency.
cytogenetic maps A map of a chromosome that locates genes with respect to chromosomal features distinguishable in a microscope.
nondisjunction An error in meiosis or mitosis in which members of a pair of homologous chromosomes or a pair of sister chromatids fail to separate properly from each other.
aneuploidy A chromosomal aberration in which one or more chromosomes are present in extra copies or are deficient in numbers.
monosomatic Referring to a diploid cell that has only one copy of a particular chromosome instead of the normal two.
trisomic Referring to a diploid that has three copies of a particular chromosome instead of the normal two.
polyploidy A chromosomal alteration in which the organism possesses more than two complete chromosome sets. It is the result of an accident of cell division.
deletion (1) A deficiency in a chromosome resulting from the loss of a fragment through breaking. (2) A mutational loss of one or more nucleotide pairs from a gene.
duplication An aberration in chromosome structure due to fusion with a fragment from a homologous chromosome, such that a portion of a chromosome is duplicated.
inversion Am aberration in chromosome structure resulting from reattachment of a chromosomal fragment in a reverse orientation to the chromosome from which it originated.
translocation The synthesis of a polypeptide using the genetic information encoded in an mRNA molecule. There is a change of “language” from nucleotides to amino acids.
down syndrome A human genetic disease usually caused by the presence of an extra chromosome 21; characterized by developmental delays and heart and other defects that are generally treatable or non life threatening.
genomic imprinting A phenomenon in which expression of an allele is inherited from the male or female parent.
Created by: lizhopper2
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