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block #3 pharm.

Thrombin Inhibitors Heparin, Fondaprinux (LMW), Warfarin
Platelet Inhibitors Aspirin, Clopidogrel
Fribrinolytics Streptokinase Coagulants/Antidotes: Protamine Sulfate, Vitamin K1
Hemostasis process that stops blood vessels form leaking after being damaged
Thrombosis formation of a blood clot inside a blood vessel
A clot is produced in three phases: 1. vascular phase 2. platelet phase 3. coagulation phase
Strategies to prevent thrombosis: 1. inhibit thrombin 2. inhibit platelet function 3. inhibit fibrin formation
Arthralgia joint pain
Myalgia pain associated with muscle injury
Urticaria hives
Emesis vomiting
Erythema redness of the skin
Dysphoria the opposite of euphoria
Salicylism condition in which toxic doses of salicylates result in nausea, tinnitus, and delerium
Arthritis inflammation of the joints
Hyperemia increased blood flow to a body part
Allergen substance capable of producing an allergic reaction
Nonselective interacts with any subtype receptor
Chronic Bronchitis a respiratory condition caused by chronic irritation that increases secretion of mucus and causes degeneration of the respiratory lining
COPD chronic obstructive pulmonary disease
Bronchodilator a drug that relaxes bronchial smooth muscle and dilates the lower respiratory passages
Asthma characterized by shortness of breath and wheezing
Oliguria production of only small amount of urine
ADH antidiuretic hormone
Dysmenorrhea painful menstruation
Petechia small area of the skin or mucus membrane that is discolored because of localized hemorrhages
Emphysema a disease in which patients have difficulty expelling air from the lungs; causes destruction of the walls of the alveoli
Rheumatic Fever condition in which pain and inflammation of joints are accompanied by elevated body temperature
Wheal firm, elevated swelling of the skin
Mucolytic a drug that liquefies bronchial secretions
Anuria production of no urine
Antigen substance that stimulates an immune response
Excoriation an abrasion of the epidermis
Histamine chemical mediator released from mast cells
Phlegm mucus
Analgesic a substance that inhibits ones reaction to pain
H1 First Generation -Diphenhydramine -Dimenhydranate -Chlorpheniramine
H1 Second Generation -Loratadine -Desloratadine -Fexofenadine -Cetirizine
H2 -Cimetidine -Ranitidine -Pepcid
Histamine is found...... throughout the body in the MAST CELLS and basophils (white blood cells)
The largest concentration of mast cells are in the..... lungs, the gastrointestinal (GI) tract, and the skin
H1: Smooth Muscle -Bronchoconstriction -intestinal cramps and diarrhea -vasodilation
H1: Nervous System -pain -itching
H2: Gastric Mucosa -Gastric acid secretion
H2: Cardiac Muscle -Stimulant effect
H3: Nervous System -pain -itching
H4: Immune System -Leukocytes (especially eosinophil)
Therapeutic use of H1 receptor antagonists: Type-1 hypersensitivity reactions allergic rhinitis, sneezing, and itching of eyes
Therapeutic use of H1 receptor antagonists: Allergic dermatoses can control itching associated with insect bites
Therapeutic use of H1 receptor antagonists: Antiemetic prevention or treatment of nausea and vomiting (anti-muscarinic effect) NOT DURING PREGNANCY
Therapeutic use of H1 receptor antagonists: Parkinson's disease reduction of tremors and muscle rigidity (anti-muscarinic effect)
Anemia: Antianemics -Ferrous sulfate -Vitamin B12 -Folic acid -erythropoietin
Anemia: Antidotes =Deferoxamine
Created by: gjtouchard
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