Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how


Fusion inhibitors Block ATTACHMENT: Maraviroc Block PENETRATION: Enfuvirtide
Integrase inhibitors Raltegravir
Protease inhibitors (-navir): Lopinavir, Atazanavir, Darunavir, Fosamprenavir, Saquinavir, Ritonavir, lndinavir
Reverse transcriptase inhibitors 1. NRTI´s 2. NNRTI´s
NRTI´s (Nucleoside Reverse Transcriptase Inhibitors) Tenofovir (TDF) Emtricitabine (FTC) Abacavir (ABC) Lamivudine (3TC) Zidovudine (ZDV,formerly AZT) Didanosine (ddl) Stavudine (d4T)
NNRTI´s (Non-Nucleoside Reverse Transcriptase Inhibitors) END E= Efavirenz N= Nevirapine D= Delavirdine
Prevent maturation of new viruses Protease inhibitors
Protease inhibitor that can "boost" other drug concentrations by inhibiting cytochrome P-450. Ritonavir
Protease inhibitors; TOXICITY 1. Hyperglycemia 2. GI intolerance (nausea, diarrhea) 3. Lipodystrophy. 4. Nephropathy 5. Hematuria (indinavir).
NRTI that´s a nucleotide analog and does NOT have to be ACTIVATED Tenofovir
NRTI used for general prophylaxis and during pregnancy to reduce risk of fetal transmission. Zidovudine (ZDV)
NRTI´s (Nucleoside Reverse Transcriptase Inhibitors); TOXICITY 1. Bone marrow suppression 2. Peripheral neuropathy 3. Lactic acidosis (nucleosides) 4. Rash (non-nucleosides) 5. Anemia (ZDV). 6. Pancreatitis (Didanosine)
Bone marrow suppression caused by NRTI´s can be reversed with Granulocyte colony stimulating factor (G-CSF) and erythropoietin
Reversibly inhibiting HIV integrase. Raltegravir (Integrase inhibitors)
Raltegravir (Integrase inhibitors); TOXICITY Hypercholesterolemia
Binds gp41, inhibiting viral entry Enfurvitide
Skin reaction at injection site Enfurvitide
Binds CCR-5 on surface of T cells/monocytes, inhibiting interaction with gp120 Maraviroc
Inhibit influenza neuraminidase, decreasing the release of progeny virus. Zanamivir, Oseltamivir
Zanamivir, Oseltamivir; CLINICAL USE BOTH Inlfuenza A and B
Inhibits synthesis of guanine nucleotides by competitively inhibiting IMP dehydrogenase Ribavirin
RSV, Chronic Hepatitis C Ribavirin
Ribavirin; CLINICAL USE RSV, Chronic Hepatitis C
Ribavirin; TOXICITY 1. Hemolytic anemia 2. Severe Teratogen
Acyclovir (Nucleoside analog); MOA Inhibits viral DNA polymerase by chain termination.
Acyclovir; CLINICAL USE 1. HSV and VZV 2. HSV­ encephalitis; Prophylaxis in immunocompromised patients.
Prodrug of acyclovir, has better oral bioavailability. Valacyclovir
Herpes zoster Famciclovir
Acyclovir; TOXICITY Obstructive crystalline nephropathy and acute renal failure if NOT adequately HYDRATED!!!
Acyclovir; MECHANISM OF RESISTANCE Mutated viral thymidine kinase
CMV Ganciclovir, Foscarnet
Ganciclovir; TOXICITY MORE toxic to host enzymes than Acyclovir 1. Leukopenia 2. Neutropenia 3. Thrombocytopenia 4. Renal toxicity
MORE toxic to host enzymes than Acyclovir Ganciclovir
Foscarnet; MOA Pyrophosphate analog
Inhibit viral Nucleic Acid synthesis 1. Guanine nucleotide synthesis: -Ribavirin (RSV, HCV) 2. Viral DNA Polymerase inhibitors: -Foscarnet (CMV) -Cidofovir (HSV Acyclovir resistant) 3. Guanosine analogs: -Acyclovir (HSV, VZV) -Ganciclovir (CMV)
Foscarnet; CLINICAL USE 1. CMV retinitis in immunocompromised patients when ganciclovir fails 2. Acyclovir-resistant HSV.
Foscarnet; MECHANISM OF RESISTANCE Mutated DNA polymerase
What decreases Cidofovir toxicity Coadminister with Probenecid and IV saline
Glycoproteins synthesized by virus-infected cells Interferons
Interferons; MOA block replication of both RNA and DNA viruses.
IFN-Alpha 1. Chronic Hepatitis B and C 2. Kaposi sarcoma 3. Hairy cell leukemia 4. Condyloma acuminatum 5. Renal cell carcinoma 6. Malignant melanoma
IFN-Beta Multiple sclerosis
IFN-Gamma Chronic granulomatous disease
Created by: heidy39



Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards