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zoo141 chap 9

muscle fatigue

QuestionAnswer
muscle fatigue part 1 (A) after peak activity, a major factor promoting fatigue is decreased pH in muscle (due especially to lactic acid accumulation
muscle fatigue part 1 (B) decreased Ca ion binding to troponin and altered enzyme activities
muscle fatigue part 2 recovery period involves conversion of lactate to pyruvate
muscle fatigue part 3 Cori cycle: liver removes lactate from blood, converts lactate to pyruvate to glucose (requires oxygen), then releases glucose into blood, which can then be taken back into muscle cells and stored as glycogen
muscle fatigue part 4 oxygen debt = excess postexercise oxygen consumption (EPOC) = amount of oxygen required to restore normal pre-exertion conditions
muscle fatigue part 4 (A) skeletal muscle: uses oxygen to restore ATP, creatine phosphate, and glycogen
muscle fatigue part 4 (B) liver: uses oxygen to generate ATP to convert lactate to glucose
Created by: btuehara
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