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Temporal Arteritis

Also called Giant Cell Arteritis

QuestionAnswer
Name some signs and symptoms of temporal arteritis. 1. new headache 2. jaw claudication 3. visual symptoms (loss of vision) 4. proximal myalgias/arthralgias 5. weight loss 6. malaise 7. fever
Another name for vasculitis of unknown etiology. Temporal Arteritis; [AKA Giant Cell Arteritis]
What kind of arteries does temporal arteritis affect? Medium to large sized arteries with internal elastic lamina
What are the preferred sites of TA involvement? Branches of internal and external carotid arteries, particularly temporal artery
Who is most effected by temporal arteritis? It is a disease of the elderly. Rarely found in ages younger than 50, and more common in females.
Name some clinical findings of temporal arteritis. 1. temporal artery tenderness or decreased pulsation 2. Visual field cuts 3. ophthalmoplegia (paralysis of occular muscles) 4. ptosis (drooping eyelid) 5. retinal or optic disc ischemia
Name some diagnostic considerations for temporal arteritis. Temporal artery biopsy Labs: CRP, CBC, CMP ESR-almost always increased, usually =/> 50. (may be normal in 15% of patients)
Differential diagnoses for temporal arteritis. 1. other forms of vasculitis, although is usually distinguishable by differences in organ involvement, clinical manifestations, age. 2. Others may include arteriosclerotic dx, malignancy, infection
Name some treatment options for TA. 1. High dose prednisone, 40-60mg/day - may require IV solu-medrol in pts with recent blindness, less than 24-36 hrs 2. clinical response is usually rapid 3. ESR normalizes in 2-4 weeks 4. Reduction of daily dose when s/s have resolved / ESR normalized
True or False? Prognosis with treatment is good. True
Risk of death from TA appears to be increased within the first 4 weeks of treatment. True or False? False. Risk of death appears to be increase within the first 4 MONTHS of treatment.
Death can occur from vascular complications such as stroke, MI, or ruptured aneurysm? True or False? True.
True or False? Remission is maintained after withdrawal of therapy in most cases? True.
Created by: MissyGirl3971