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cardiovascular syste
| Term | Definition |
|---|---|
| form and function of blood in cv system | transportation, defense, and regulatory functions |
| transportation | oxygen, nutrients, waste, carbon dioxide, and hormones |
| defense | against invasions by pathogens |
| regulatory functions | body temperature, water-salt balance and body PH 7.45 |
| composition of blood | blood is a fluid connective tissue, formed elements in red bone marrow, white blood, red blood cells and platelets |
| plasma | 91% water and 9% salt ions and organic molecules and the most abundant molecules |
| 3 major types of plasma proteins | Albumins, Globulins, and fibrinogen |
| Albumins | most abundant and important for plasma's osmatic pressure as well as transportation |
| Globulins | also important to transportation |
| Fibrinogen | important for the formation of blood |
| RBC (form an function) four to six million mm3 | structure of red blood cells, lack a nucleus and few organelles, biconcave shaped increases surface area, |
| RBC | HB hemoglobin contain 4 highly folded polypeptide chains. the heme is the the iron portion in the center of the peptide reversibly binds O and CO2 contain 280 mill heme that bind 4 molecules of O2thus red blood carry over 1 billion oxygen mollecule |
| Carbon dioxide is transported as | 68% bicarbonate ion in the plasma(conversion take place in RBC) 25%in red blood cells and 7% carbon dioxide in the plasma |
| production of red blood cells | in red bone marrow, lifespan about 120 days, sicklecell 90, erythropoietin(epo),old cells are destroyed by liver. |
| Erythropoietin | excreted by kidney cells and moves to red marrow when oxygen levels are low |
| Blood doping | any method of increasing RBC to increase athletic performance, more efficient delivery of oxygen and fatigue, EPO injected months before event,able to cause death due thickening of the blood that leads to heart attack |
| RBC disorders are | Anemia, sickle-cell anemia, and hemolytic disease |
| Anemia | condition resulting to few RBC or hemoglobin that cause run down feeling(iron,B12, B, and folic acid) |
| Sickle cell | genetic disease that cause RBC to be sickle shaped that tend to rupture |
| Hemolytic | newborn-a condition with incompatible blood types that lead to rupturing of blood cells in a baby before and continuing after birth |
| White blood cells 5,000 to 11,000 | from red bone marrow and are large blood cells that have nucleus, regulated by colony stimulating factor(CSF)found in blood and in tissue(move through capillary walls,fights infection nd important of the immune sys. live days,months and years |
| Granular | Eosinophil, Basophil, and neutrophil |
| Agranular | lymphocyte, and monocyte |
| WBC disorders | severe combined immunodeficiency disease SCID-an inherited disease in the the stem cells of WBC lack an enzyme that allows them to fight infection. |
| Leukemia | a group of cancers that affect white blood cells in which cells proliferate without control |
| Infectious mononucleosis | known as the kissing disease, occurs when the Epstein-Barr virus EBV infects lymphocytes resulting in fatigue, sore throat and swollen lymph nodes |
| Platelets form 150,000 to 300,000mm3 | made of fragments of large cells called megakaryocytes made in the red bone marrow, 200 bill per day function in blood clotting, b proteins named thrombin and fibrinogen important for blood clotting leading to fibrin threads that catch RBCs |
Created by:
msmimi
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