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zoo141 Chapter 5

NAILS/age related skin changes/hormonal effects/skin repair

QuestionAnswer
nail body visible portion of nail
nail root portion of nail lying underneath skin
lunula pale crescent of nail near root
nail bed epidermis beneath nail
eponychium part of stratum corneum overlying proximal part of nail
hyponychium part of stratum corneum underneath distal part of nail
decreased germinative cell activity epidermis thins
decreased sebaceous and sweat gland activity decreased perspiration, drier skin
decreased melanocyte activity gray/white hairs, increased sunburn risk
decreased number of dendritic cells decreased immune response
decreased number of active hair follicles fewer hairs
decreased blood flow to dermis decreased ability to lose body heat
[Hormonal effects on integument] thyroid gland hormones maintain blood flow to dermis
[Hormonal effects on integument] glucocorticoids loosen connections between keratinocytes
[Hormonal effects on integument] sex hormones, epidermal growth factor stimulate epidermal cell divisions
[Hormonal effects on integument] growth hormone stimulates fibroblast activity and collagen synthesis
[Steps in integumentary repair] initial injury bleeding, mast cells release histamine
histamine inflammatory response
[Steps in integumentary repair] after several hours a. blood clot → scab, b. macrophages phagocytize debris, c. granulation tissue starts to form
[Steps in integumentary repair] after one week a. epidermal cells migrate underneath scab, b. fibroblasts produce collagen fibers in dermis
[Steps in integumentary repair] after several weeks a. epidermal repair is complete, b. scar tissue completes repair process in dermis
Created by: btuehara
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