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Drugs MP Test 1

QuestionAnswer
Blocks VR Na+ channels made by puffer fish. Tetrodotoxin
Blocks VR Na+ channels made by marine invertebrates. Causes paralysis. Saxitoxin
Blocks VR K+ channels. Made by mamba snake venom Dendrotoxin
Stretches from M line to z line. Stabilizes the position of the filaments of the sarcomere. Has elasticity Titin
Spans the length of thin filament. Alligns the thin filaments in the correct position Nebulin
Anchors the myofibrils to the cell membrane Dystrophin
line in sarcomere that never changes deminsions. Actual length of thick filament A band
Only thin filament I band
Only thick filament H zone
inhibits ACHase activity causes convulsions can be lethal - agonist physostigmine
Inhibits ACHase doesnt enter spinal chord has effects at NJ used for patients with myasthenia gravis neostigmine
causes flood of ACH black widow venom
inhibits breakdown of ACH causes convulsions and problems breathing Organophosphates
binds to nicotinic receptors and cause depolarization nicotine
produced by clostridium botulinum blocks release of ACH attaches and degrade SNAP 25 complex. Paralizes the muscle botox
binds to ACH receptor no action potential curare
binds to ACH receptor and causes initial depolarization and then stops. Used in hospitals to relax muscles succynylcholine
causes skeletal muscle weakness and deteriation. Muscle replaced by fatty and fibrous tissue muscular dystrophy
autoimmune disease causes reduction in active ACH receptor. Myasthenia gravis
Created by: twp0001
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