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EMT Pharmacology
EMT NAIT Medication administration- Terms
| Term | Definition |
|---|---|
| The 6 "Rights" of medication administration | Right Patient Right Medication Right Dose Right Time Right Route Right Documentation |
| Enteral Route | Oral, Rectal, naso/orogastric |
| Percutaneous Route | Topical (transdermal) Sublingual Buccal Ocular nasal Aural (ear) |
| Parenteral Route | Intradermal Subcutaneous (SQ/SC) Intramuscular (IM) Intravenous (IV) Intraosseous (IO) Intramuscular (IM) Intravenous (IV) Intraosseous (IO) |
| Pulmonary Route | Inhalation (MDI/Nebulizer) Endotracheal (paramedic scope) |
| Movement of drugs in the body as they are absorbed, distribution, metabolized and excreted | Pharmacokinetics |
| Nature of absorbing surface, blood flow to site of administration, solubility of the drug, Ph, Drug concentration, dosage form, route of entry, bioavailability | Factors affecting Absorption |
| Diffusion, Osmosis, Filtration | Mechanisms involved in Absorption |
| The transport of an absorbed drug to target site | Distribution |
| A series of chemical alterations drugs undergo within the body- in preparation for excretion | Biotransformation |
| Elimination of the waste products of drug metabolism | Excretion |
| The study of effects on the body | Pharmacodynamics |
| Plasma Level Profile, Biological Half Life, Therapeutic Threshold, Therapeutic Index | Drug response factors |
| The time it takes for plasma level of a drug to decrease to half the measured amount | Half Life |
| Age body mass gender environment and time of administration existing pathology | Factors altering Drug Responses |
| symptoms that mimic naturally occurring disease states | Iatrogenic Response |
| Synergism | Two drugs working together |
| Potentiation | One drug multiplying or prolongs effects of another |
| Antagonist | drug that prevents receptor stimulation by binding to a receptor site |
| Hypersensitivity | AKA drug allergy |
| Idiosyncratic reaction | abnormal or unexpected reaction peculiar to a certain patient |
| Tolerance | individual capacity to endure certain medication- require larger dosage to achieve desired response |
| Drug allergy | reaction occurring in a person who has been previously exposed to a drug and has developed antibodies |
| Delayed reaction (serum sickness) | a type of hypersensitivity |
| Anaphylactic reaction | Acute, systemic allergic reaction |
| Cross tolerance | increased tolerance to drugs in the same class/family |
| Drug dependance | physical or psychological need to use a drug or substance regularly |
| Tachyphylaxis | A rapid development or tolerance |
| Cumulative effect | successively stronger, larger or more effective- result from several doses administered or when absorption is faster than metabolism/excretion |
| Drug toxicity | result of overdosage, ingestion of a drug not intended for internal use or buildup of a drug in system due to impaired metabolism or excretion |
| Drug Names | chemical, trade, generic, "official" (official name is how it is listed in reference material) |
| Body system | what system of the body does a drug affect |
| Class of agent | What class is the drug |
| mechanism of action | how does this drug work on the body |
| actions, pharmacokinetics, indications | physiological action of the drug, reasons why drug is given |
| contraindications/interactions | reasons why not to give a drug |
| Dosage | amount/range of amount of drug to give based on indications/age/weight of patient |
| Route of administration | how to deliver specific medications |
| Plant sources | Alkaloids (ie:atropine, morphine) Glycosides (ie:Digitalis) Gums (ie:xanthan-used as a suspending agent) Oils (ie:eucalyptus) |
| Animal sources | oxytocin, insulin, some vaccines, some birth control |
| Mineral sources | Iodine, calcium, iron, sodium bicarbonate, calcium chloride, magnesium sulphate |
| Synthetic sources | Lidocaine, diazepam, demerol, |
| Microorganisms | some antibiotics such as penicillin, streptomyocin |
| Teratogenic | any agent that interferes with or alters the normal development of a fetus with results that are evident at birth |
| Polypharmacy | unwanted duplication of drugs- common in elderly patients that have multiple medications |
| Therapeutic Index | comparison of the amount of medication that causes the therapeutic effect with the amount that causes toxic effect |