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FA: Treatments
from Rapid Review: Classic/Relevant Treatments
| Question | Answer |
|---|---|
| absence seizures | ethosuximide |
| acute gout attack | NSAIDS, colchicine |
| acute promyelocytic leukemia [M3] | all-trans retinoic acid |
| ADHD | methylphenidate, amphetamines |
| alcohol abuse | AA + disulfiram for pt and Al-Anon for family |
| alcohol withdrawal | benzodiazepines |
| anorexia or bulimia | SSRIs |
| anticoagulation during pregnancy | heparin |
| arrhythmia in damaged cardiac tissue | class 1B antiarrhythmic [lidocaine, mexiletine, tocainide] |
| B12 deficiency | vit B12 supplements. work up cause w/ Schilling test |
| BPH | tamsulosin, finasteride |
| bipolar disorder | lithium, valproate, carbamazepine, lamotrigine [mood stabilizers] |
| breast cancer in postmenopausal woman | aromatase inhibitor [anastrozole] |
| buerger's disease [thromboangiitis obliterans] | stop smoking! |
| candida albicans | ampho B [systemic], nystatin [oral thrush/esophagitis] |
| carcinoid syndrome | octreotide |
| chlamydia trachomatis | doxycycline [add ceftriaxone for gonorrhea coinfection]. erythromycin eye drops [prophylaxis for infants] |
| chronic gout | probenecid [underexcretor], allopurinal [overproducer] |
| chronic hepatitis | IFN-alpha |
| CML | imatinib |
| c. botulinum | antitoxin |
| c. diff | oral metronidazole [oral vancomycin if refractory] |
| c. tetani | antitoxin + vaccine booster + diazepam |
| crohn's disease | corticosteroids, infliximab |
| cryptococcus neoformans | fluconazole [prophylaxis in AIDS pt] |
| cyclophosphamide induced hemorrhagic cystitis | mesna |
| cystic fibrosis | N-acetylcysteine [Mucomyst] + antipseudomonal prophylaxis [tobramycin/azithromycin] |
| CMV | ganciclovir |
| depression | first line = SSRIs |
| diabetes insipidus | central: desmopressin. nephrogenic: HCTZ, indomethacin, amiloride |
| DM type 1 | low sugar diet + replace insulin |
| DM type 2 | diet intervention, oral hypoglycemics, possible insulin |
| DKA | fluids, insulin, potassium |
| enterococci | vancomycin/ampicillin + aminoglycoside |
| erectile dysfunction | sildenafil, vardenafil |
| ER+ breast cancer | tamoxifen |
| ethylene glycol/methanol intoxication | fomepizole [ETOH dehydrogenase inhibitor] |
| Hib | rifampin prophylaxis |
| generalized anxiety disorder | buspirone |
| acute heparin toxicity | protamine sulfate |
| HER2/neu+ breast cancer | trastuzumab |
| hyperaldosteronism | spironolactone |
| hypercholesterolemia | first line = statin |
| hypertriglyceridemia | fibrate |
| immediate anticoagulation | heparin |
| infertility | leuprolide, pulsatile GnRH |
| influenza | rimantadine, oseltamivir |
| legionella pneumo | erythromycin |
| long term anticoagulation | warfarin |
| malaria | chloroquine [for blood schizont. mefloquine if resistant]. primaquine [for liver hypnozoite, relapses] |
| malignant hyperthermia | dantrolene |
| medical abortion | mifepristone |
| migraine | sumatriptan |
| MRSA | vancomycin |
| multiple sclerosis | beta interferon, immunosuppression, natalizumab |
| MTB | RIPE [rifampin, INH, pyrazinamide, ethambutol] |
| N. gonorrhea | ceftriaxone [add doxycycline for coinfection w/ Chlamydia] |
| N. meningitis | PCN/ceftriaxone. prophylaxis = rifampin |
| neural tube defect prevention | prenatal folic acid |
| osteomalacia/rickets | vit D supplements |
| osteoporosis | bisphosphonates. Ca and vit D supplements |
| PDA | indomethacin [to close]. PGE2 to keep it open |
| pheochromocytoma | alpha antagonists [phenoxybenzamine]. phentolamine to Dx pheochromocytoma |
| pneumocystis jirovecii | TMP-SMX [prophylaxis in AIDS pt] |
| prolactinoma | bromocriptine [DA agonist] |
| prostate cancer/uterine fibroids | leuprolide, continuous GnRH |
| prostate carcinoma | flutamide |
| pseudomonas aeruginosa | antipseudomonal PCN + aminoglycoside |
| idiopathic pulmonary arterial HTN | sildenafil, bosentan, epoprostenol |
| rickettsia rickettsii | doxycycline, chloramphenicol [esp. if pt has aplastic anemia] |
| ringworm infections | terbinafine, griseofulvin, imidazole |
| schizophrenia [negative symptoms] | 5-HT2 antagonists [2nd gen antipsychotics] |
| schizophrenia [positive symptoms] | D2 receptor antagonists [1st and 2nd gen antipsychotics] |
| SIADH | demeclocycline, lithium, ADH receptors antagonists |
| sickle cell anemia | hydroxyurea [increase fetal Hgb] |
| sporothrix schenckii | oral KCl |
| stable angina | sublingual nitroglycerin |
| staph aureus | MSSA: nafcillin, oxacillin, dicloxacillin. MRSA: vancomycin |
| strep bovis | PCN prophylaxis. if linked to endocarditis: evaluate for colon cancer |
| strep pneumo | PCN/cephalosporin [systemic infection, pneumonia], vancomycin [meningitis] |
| strep pyogenes | PCN prophylaxis |
| temporal giant cell arteritis | high dose steroids |
| tonic clonic seizures | phenytoin, valproate, carbamazepine |
| toxoplasma gondii | sulfadiazine + pyrimethamine |
| treponema pallidum | PCN |
| trichomonas vaginalis | metronidazole [pt + partner] |
| ulcerative colitis | 5-ASA, infliximab |
| UTI prophylaxis | TMP-SMX |
| warfarin toxicity | acute: FFP. chronic: vit K |
| wegener's granulomatosis w/ polyangiitis | cyclophosphamide, corticosteroids |