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Male Reproductive and Genitourinary Tumors

High gleason score for prostate cancer Poorly differentiated tumor, thus worse prognosis (Mosbys pg. 186)
Most common site of distant metastasis for prostate cancer Bone (Mosbys pg. 185)
Prostate Specific Antigen Found in seminal vesicle fluid and plasma that is produced by benign and malignant cells (V/D pg. 150)
Pattern of lymphatic spread for prostate cancer Periprostatic and obturator nodes first involved followed by external iliac, hypogastric, common iliac, and periaortic nodes (W/L pg. 824)
75% of prostate cancers present in this location of the gland Peripheral zone
Narrowing of opening of the prepuce that may cause penile cancer Phimosis (W/L pg. 839)
White secretion that collects under the prepuce of the foreskin Smegma (W/L pg. 839)
Most common site of metastatic spread for penile cancer Inguinal nodes (W/L pg. 841)
Causes of testicular cancer Cryptorchidism, Klinefelter syndrome, Mumps orchitis (Mosbys pg. 186)
Most common histology of testicular cancers Seminoma (V/D pg. 158)
Most common lymph nodes involved in testicular cancer Periaortic nodes along the lumbar vertebra and below the kidneys (V/D pg. 159)
Hockey stick treatment field Seminomas with periaortic and ipsilateral inguinal area involvement (V/D pg. 161)
Radiation dose for seminomas Very low (25 Gy) because of their extreme radiosensitivity (V/D pg. 160)
Signs and symptoms of painless mass/swelling, gynecomastia, infertility, back pain Testicular cancer (Mosbys pg. 186)
Treatment techniques for seminomas Orchiectomy followed by external beam radiation (V/D pg. 160)
Treatment techniques for nonseminomas Orchiectomy followed by cisplatin based chemotherapy (W/L pg. 852)
Von Hippel Lindau disease associated with this type of cancer Renal cell cancer (W/L pg. 854)
Location of kidneys Retroperitoneal space between 11th rib and transverse process of L3- right kidney usually 1 to 2 cm lower than left (W/L pg. 854)
Most common sign of renal cell carcinoma Gross or microscopic hematuria (W/L pg. 855)
Gerota’s fascia Envelops kidney in its fibrous capsule and perinephric fat (W/L pg. 854)
Most common location of bladder cancer Trigone (V/D pg. 145)
First route of spread for bladder carcinoma Direct extension in and through bladder walls and muscle (Mosbys pg. 192)
Common lymphatics involved with bladder cancer Common, external, internal iliac, and obturator (Mosbys pg. 192)
Distant metastasis of bladder cancer First to bone then to liver, lung, and rarely skin (Mosbys pg. 192)
Location from which kidney cancers usually arise Renal cortex (Mosbys pg. 280)
Histology of cancers manifesting in renal pelvis Transitional cell (Mosbys pg. 280)
Histology of cancers manifesting in renal cortex Adenocarcinoma (Mosbys pg. 280)
Intravenous pyelogram Diagnostic study for kidney cancer (W/L pg. 855)
Chemotherapy agents used to treat transitional cell carcinoma of bladder, ureter, or renal pelvis MVAC- methotrexate, vinblastine, Adriamycin, cisplatin (W/L pg. 857)
Cause of death from bladder cancer Liver failure and uremia (Mosbys pg. 192)
Created by: cb4945
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