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Drugs Used for Pain
| Question | Answer |
|---|---|
| drugs that relieve pain without producing loss of consciousness or reflex activity | analgesics |
| pain that results from injury to the peripheral or CNS | neuropathic pain |
| aka pain perception | nociception |
| pain that originates from the skin, bones, joints, muscles, or connective tissue | somatic pain |
| abbreviated NSAID | nonsteroidal antiinflamatory drug |
| a series of receptors located within the CNS that control pain | opiate receptors |
| chemicals released during trauma that contribute to pain | histamine, prostaglandins, serotonin, leukotrienes, substance P, bradykinins |
| drug of choice for the treatment of severe, chronic pain | morphine sulfate |
| drugs that reverse the respiratory depression caused by excessive doses of opiate agonists, opiate partial agonists, and propoxyphene | opiate antagonists: naloxone: Narcan |
| drugs that reverse the respiratory depression caused by excessive doses of opiate agonists and opiate partial agonists | opiate antagonists: nalmefene: Revex |
| drugs that reduce cravings of opioids and alcohol | opiate antagonists: naltrexone: ReVia |
| most common analgesics used for the relief of slight to moderate pain | salicylates |
| drugs that reduce frequency of TIA, stroke, or MI | salicylates: aspirin: Zorprin, A.S.A., Empirin |
| in normal therapeutic doses, salicylates may produce these side effects | GI irritation, occasional nausea, and gastric hemorrhage |
| drug class that is a substitute for aspirin; reduce pain, inflammation, and fever | NSAIDs |
| substitute for aspirin; reduce pain and fever, but NOT inflammation | acetaminophen: Tylenol, Datril, Tempra |
| this misc. analgesic has no side effects when used as directed | acetaminophen: Tylenol, Datril, Tempra |
| drug class used to relieve acute or chronic moderate to severe pain | opiate agonists |
| drug class used for the short-term relief (up to 3 weeks) of moderate to severe pain | opiate partial agonists |
| this misc. analgesic relieves mild to moderate pain associated with muscular spasms, premenstrual cramps, bursitis, minor surgery and trauma, headache, and labor and delivery | propoxyphene: Darvon |