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PSYC SSRIs
SSRIs for Depression and Anxiety
SSRIs for Depress and Anxiety | Drug name |
---|---|
Fluoxetine | Prozac |
Sertraline | Zoloft |
Paroxetine | Paxil |
Citalopram | Celexa |
Fluvoxamine | Luvox |
Side effects SSRIs | Sexual, GI distress, agitation, insomnia, tremor, diarrhea |
Toxicity? | Serotonin syndrome: fever, myoclonus, mental status changes, CV collapse) |
How toxicity? | If taken with MAOI, increases serotonin b/c one inhibits reuptake and other inhibits degradation |
How is MAOI toxicity precipitated? | Eating foods with tyramine (red wine, cheese) b/c it is broken down by MAO but if inhibited it will increase to toxic levels |