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PSYC SSRIs
SSRIs for Depression and Anxiety
| SSRIs for Depress and Anxiety | Drug name |
|---|---|
| Fluoxetine | Prozac |
| Sertraline | Zoloft |
| Paroxetine | Paxil |
| Citalopram | Celexa |
| Fluvoxamine | Luvox |
| Side effects SSRIs | Sexual, GI distress, agitation, insomnia, tremor, diarrhea |
| Toxicity? | Serotonin syndrome: fever, myoclonus, mental status changes, CV collapse) |
| How toxicity? | If taken with MAOI, increases serotonin b/c one inhibits reuptake and other inhibits degradation |
| How is MAOI toxicity precipitated? | Eating foods with tyramine (red wine, cheese) b/c it is broken down by MAO but if inhibited it will increase to toxic levels |