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PSYC Anxiolytics

First Aid USMLE 2 Anxiolytics

AnxiolyticsDrug nameIndicationsSide EffectsMechanismWhat you should remember...
SSRIs Fluoxetine, Sertraline, Paroxetine, Citralopram, Escitalopram First line for GAD, OCD and PTSD Nausea, GI upset, somnolence, sexual dysfunction, agitation Blocks serotonin reuptake to increase serotonin
Buspirone Buspirone GAD, OCD, PTSD SEIZURES with chronic use. NO tolerance, withdrawal or dependence. Unknown Takes 1 week before action
Beta blockers Atenolol, metoprolol, propranolol Performance anxiety, PTSD bradycardia, hypotension blocks beta receptors found throughout the body: heart beta1 decrease HR and BP, lungs beta2 bronchoconstriciton (blank)
Benzodiazepines Lorazepam (ativan), Alprazolam (xanax) Anxiety, insomnia, alcohol withdrawal, muscle spasm Decrease sleep duration; risk of abuse, tolerance and dependence Binds GABA receptors and increases affinity for GABA to cause depression (blank)
Flumazenil Romazicon Antidote to benzo intoxication resedation; nausea, dizziness, vomiting and pain at injection site blocks benzo binding at GABA receptor (blank)
Created by: MatAnt