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| Term | Definition |
|---|---|
| CODIS | (Combined DNA Index System) The generic term used to describe the FBI’s program of support for criminal justice DNA databases as well as the software used to run these databases. |
| RFLP | Restriction fragment length polymorphism, is a technique that exploits variations in homologous DNA sequences |
| Sticky Ends | A fragment of DNA in which the terminal portion has a stretch of unpaired nucleotides, and the strands are not of the same length. |
| DNA Fingerprinting | The method of isolating and making images of sequences of DNA. |
| Cleave | To split or sever |
| DNA | Deoxyribonucleic acid is a molecule that encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses. |
| Comb | |
| Restriction Enzyme | An enzyme produced chiefly by certain bacteria, having the property of cleaving DNA molecules at or near a specific sequence of bases. |
| Exclusion | The act or practice of excluding. |
| Hybridization | The act of mixing different species or varieties of animals or plants and thus to produce hybrids. |
| VNTR | a tandem repeat from a single genetic locus in which the number of repeated DNA segments varies from individual to individual and is used for identification purposes. |
| Nucleotides | A nucleotide is an organic molecule made up of a nucleotide base, a five-carbon sugar (ribose or deoxyribose) and at least one phosphate group. Nucleotides make up the basic units of DNA and RNA molecules. |
| Gel Lanes | |
| DNA Fragments | The seperated or broken pieces of DNA. |
| Palindrome | In molecular biology, a self-complementary nucleic acid sequence; a sequence identical to its complementary strand, if both are “read” in the same 5′ to 3′ direction, or inverted repeating sequences running in opposite directions (5′-AGTTGA-3′) on either |
| Wells | Enclosed spaces for receiving and holding something. |
| STR | Short Tandem Repeat Polymorphism. Short sequences of DNA, normally of length 2-5 base pairs |
| Electric Field | a region around a charged particle or object within which a force would be exerted on other charged particles or objects. |
| Inclusion | a foreign substance, either liquid or solid, usually of minute size, inclosed in the mass of a mineral. |
| Microliter | A unit of volume that is equal to one millionth of a liter. |
| Human Genome | The human genome is the complete set of genetic information for humans. |
| Blunt Cut | |
| Buffer | A solution containing either a weak acid and its salt or a weak base and its salt, which is resistant to changes in pH. |
| Recombinant DNA | DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) to bring together genetic material from multiple sources, creating sequences that would not otherwise be found in biological organisms. |
| DNA Polymerase | a cellular or viral polymerase enzyme that synthesizes DNA molecules from their nucleotide building blocks. |
| Gene | a unit of heredity that is transferred from a parent to offspring and is held to determine some characteristic of the offspring. |
| Digital Micropipet | A digital pipette designed for the measurement of very small volumes. |
| Staggered Cut | The cleavage of two opposite strands of duplex DNA at points near one another. |
| Agarose Gel | Agarose gel electrophoresis is a method of gel electrophoresis used in biochemistry, molecular biology, and clinical chemistry to separate a mixed population of DNA or proteins in a matrix of agarose. |
| Inconclusive | not leading to a definite decision, or result. |
| Fingerprint | An impression or mark made on a surface by a person's fingertip, esp. as used for identifying individuals from the unique pattern of whorls and lines. |
| Luminol | Luminol is a versatile chemical that exhibits chemiluminescence, with a striking blue glow, when mixed with an appropriate oxidizing agent. |
| PCR | a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in skeletal muscle and the brain. |
| Restriction Site | The specific sites at which a restriction enzyme will cleave DNA. |
| Gel Electrophoresis | A method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge. |
| Evidence | A thing or things helpful in forming a conclusion or judgment. |