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Hematological Systems

Anemia too few RBC's
Polycythemia too many RBC's
Leukopenia too few WBC's
Leukocytosis too many WBC's
Thrombocytopenia too few platelets
Thrombocythemia too many platelets
carry oxygen & nutrients, transport hormones, remove wastes, deliver cells to prevent infection, stop bleeding, promote healing hematopoetic functions
Lymphadenopathy enlargement of lymph nodes
Splenomegaly enlargement of spleen
increased platelet formation, increased clotting activity hypercoagulability
immature WBC's taking over "shift to the left"
see these cells in "shift to the left" polymorphonuclear leukocyte (segmented neutrophils)
composed of fibrin and blood cells blood clot
blocks flow to distal tissues blood clot
a blood clot that breaks away from vessel wall embolus
autoimmune disease in which blood does not clot as it should (platelets are destroyed in spleen) Idiopathic Thrombocytopenia Purpura (ITTP)
promote coagulation & stops bleeding from damaged blood vessels clotting factors
vitamin K deficiency, reduction in clotting factors due to liver disease impaired clotting
syndrome of uncontrolled bleeding resulting from systemic multiple clots (due to depletion of clotting factors) Disseminated Intravascular Coagulation (DIC)
organ that filters blood and removes unwanted material spleen
X-linked recessive disorder where no factor VIII is generated, leading to excessive bleeding Hemophilia A
disorder that decreases platelet stickiness Von Willebrand Disease
manifestations of DIC hemorrhage from every opening, abdominal distention, hematuria (blood in urine)
diagnosis and treatment of DIC accelarated clotting, decreased platelet count, removal of primary event, heparin if organ failure from hypoxemia, plasma with factor VIII
clinical manifestations of anemia increased HR and RR, dizziness, fatigue, skin pallor, nausea, decreased hair and skin quality
anemia due to loss of blood hemorrhagic anemia
whole blood is used for this type of anemia hemorrhagic anemia
type of anemia caused by excessive destruction of RBC's (bone marrow unable to compensate) hemolytic anemia
type of anemia caused by hemoglobin "S" sickle cell anemia
sickling happens in respone to... hypoxia (lack of oxygen)
type of anemia caused by dysfunction of bone marrow to replace dying cells; consequently all blood cell types are affected aplastic anemia
type of anemia caused by lack of intrinsic factor, a substance needed to absorb vit B-12 from stomach (vit B-12 is need for RBC production) pernicious anemia
most common type of anemia iron deficiency anemia
low white blood count (1000 or less) neutropenia
caused by Epstein-Barr virus, that infects B lymphocytes mononucleosis
swolen lymph nodes, severe sore throat and fever, overwhelming fatigue mononucleosis
cancer of one class of WBC in bone marrow resulting in proliferation of that cell type to the exclusion of others leukemia
acute leukemia poorly differentiated cells
chronic leukemia well differentiated cells
acute lymphoblastic leukemia (ALL) childhood leukemia
acute myeloblastic leukemia usual onset after 60 years old
chronic lymphoblastic leukemia (CLL) disease of the elderly
chronic myeloblastic leukemia (CML) worst kind of leukemia (median survival 3-4 years)
symptoms of leukemia anemia, neutropenia, thrombocytopenia
Hodgkin's Disease presence of Reed-Sternberg cell, spreads predictably
cancer of the lymph Hodgkin's Disease(s)
Non-Hodgkin's Disease no R-S cell, spreads unpredictably
cancer of the plama cells in bone marrow multiple myeloma
bone pain, Bence Jones proteins found in urine, fractures, recurrent infections multiple myeloma
Created by: lcazgirl