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hypersensitivity rxn

First Aid hypersensitivity rxns

disorderhypersensitivity rxn type
anaphylaxis I
allergic rhinitis (hay fever) I
asthma I
eczema I
hemolytic anemia II
erythroblastosis fetalis II
Goodpasture's II
bullous pemphigoid II
Grave's II
polyarteritis nodosum III
post-strep GN III
serum sickness III
arthus rxn III
hypersensitivity pneumonitis III
DM type I IV
Guillain-Barre syndrome IV
Hashimoto's IV
graft-vs-host dz IV
contact dermatitis IV
IgE mediated - free Ag cross-links IgE on presensitized mast cells and basophils --> trigger release of vasoactive amines I
Ab mediated - IgM, IgG bind fixed Ag on enemy cell --> lysis by complement or phagocytosis II
immune complex mediated - Ag-Ab complex activates complement --> attract neutrophils --> neutrophils release lysosomal enzymes III
delayed (T-cell) mediated - sensitized T lymphocytes encounter Ag --> release lymphokines --> macrophage activation IV
Created by: anpham26



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