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Vocab

ch 16

TermDefinition
Mendel learns about DNA (1875)
Frederick Griffith look at pathogenic Bacteria (1928)
Avery, McCarty, Mcleod DNA exchanged in bacterial transformation (1944)
Erwin Chargaff discovered % A,T,C,G different among different species (1947)
Hershey & Chase showed DNA was the vehicle of hereditary (1952)
Rosalind Franklin took X-ray diffraction of DNA (1950s)
James Watson & Francis Crick saw images, found double helix, & found phosphate had to be on outside of molecule/ Purine & Pyrimidine= width consistent (1950s)
1st Paper published in 1953 won Nobel prize (1962)
2nd Paper published 1954 describes how DNA replicates= 3 steps
DNA replication 3 steps from paper 1-separation 2-put in new nucleotides 3-2 replicated DNA
Origin of Replication particular sequence on the DNA molecule where replication begins
Replication Bubble where open from origin
Replication Fork end of bubble (opening)
Step 1 of Replication opening up/untwisting DNA
Helicase enzyme that untwists & separates the double helix
Single Strand Binding Protein binds to the single strands as replication fork opens stabilize the separated single strands of the template DNA
Topoisomerase relieves the strain on the (cuts) DNA as helicase untwists the helix
Step 2 of Replication Priming
DNA Polymerase enzyme that build new polymer of DNA (add nucleotides to a growing strand)
Primer chunk of RNA
Primase enzyme that adds RNA
Step 3 of Replication Elongation-DNA polymerase adds neuclotides to 3' end
Okazaki Fragments synthesis of 5' end in short chunk
Created by: 100000779212541
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