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Bio219 Exam 2
Exam2
| Question | Answer |
|---|---|
| 1. Organismal complexity is correlated to which of the following? | Is not correlated to genome size, number of genes in the genome, or amount of repetitive DNA in the genome |
| 2. If two genomes were compared by a CoT curve, a less complex genome will reanneal ________________ than a more complex genome. | Faster |
| 3. Which of the following is most useful for forensic DNA analysis? | Highly-repetitive mini-satellites |
| 4. In the Avery, McCarty and MacLeod experiment, which of the following pieces of data showed that DNA is the 'transforming' material? | When treated with DNase, transformed bacteria were no longer able to grow on plates. |
| 5. Based on Chargaff's rules, which of the following statements is true? | (%purines)/(%pyrimidines) = 1 |
| 6. A major difference between B-DNA and Z-DNA is: | B-DNA is right-handed, while Z-DNA is left-handed |
| 7. Which of the following is necessary to build a nucleosome? | ~150bp of DNA & 8 histone proteins |
| 8. Cargo can be exported from the nucleus when which of the following is true? | Exportin is bound to Ran-GTP |
| 1. If a DNA sequence reads 3' - AATTGGCC - 5', which nucleotide will be closest to the bottom on a Sanger Sequencing (Chain-termination sequencing) gel? | T |
| 2. The major advantage of next generation sequencing is that all methods: | are massively parallel |
| 3. One difference between the Ion Torrent and the SMRT technologies is that: SMRT technologies is that: | one detects hydrogen ions while the other detects fluorescent bases. |
| 4. If the recombination distance between A and B is: 25cM and between B and C is: 17 cM and between A and C is: 8cM, then the order of the genes on the chromosome is: | ACB |
| 5. Which of the following methods was used by the government to sequence the human genome in the Human Genome Project? | Templated Sequencing and Chain-termination sequencing |
| 6. A complementation experiment could show: | whether genes have been transferred between bacteria |