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Disorder Features
Features of CLC disorder
| Question | Answer |
|---|---|
| William’s: Shown faces: amygdala | less reactivity |
| William’s: Happy/Neutral vs Fearful/Neutral faces: amygdala | more reactivity than controls to happy, hypo-active to fearful |
| Williams’s: Fearful faces vs. Aversive non human stimuli: amygdala | higher response to non human stimuli |
| William’s: where are they better than Down Syndrome? | remembering numerical sequences, describing an elephant, identify cooperation, vocabulary, effective language |
| William’s: where are they worse than Down Syndrome? | drawing an image (visiospatial) |
| William’s: What region accounts for the selective sparing? | dlPFC, using verbal skills to inhibit the amygdala |
| Psychopaths: fear conditioning: amygdala | no amygdala response, no conditioning |
| Psychopaths: fear conditioning: cortex | normal, can identify which is supposed to be aversive |
| Psychopaths: the “better” ones are different in what brain way? Why? | they can condition to fear and use hypercognition to regulate emotions |
| Antisocial + CU: faces: amygdala | lower response |
| Antisocial + CU: fearful vs neutral faces: amygdala | less response to fear |
| Antisocial + CU: fearful faces: eye gaze | doesn’t look at eyes |
| Autism Spectrum: fearful face: eye gaze | doesn’t look at eyes |
| Autism Spectrum: facial processing technique | not gestalt (one feature at a time) |
| Autism Spectrum: inverted faces | process on the same timing |
| Autism Spectrum: Temple Grandin feels like | a prey animal |
| Autism Spectrum: congruent vs incongruent facial trials: how do they do? | faster than control on congruent |
| Autism Spectrum: congruent vs incongruent facial trials: what brain region is important | NBM, to increase sensitivity and therefore reaction time |
| Autism Spectrum: judge man or woman: reaction time | normal |
| Autism Spectrum: habituation to faces: amygdala | do not habituate, novelty remains, amygdala response doesn’t change |
| Intermittent Explosive Disorder: shown anger: amygdala | hyperreactive |
| Intermittent Explosive Disorder: amygdala & vmPFC connectivity | decreased |
| Intermittent Explosive Disorder: angry faces: amygdala | more dorsal output than ventral input |
| Intermittent Explosive Disorder: fearful faces: amygdala | no difference in input and output |
| GAD: fearful faces: amygdala | hyper reactivity |
| GAD: anticipatory anxiety to aversive images | way increased |
| GAD: threat of shock: what brain region maps this? | BNST |
| Specific Phobias: phobic stimuli: amygdala | hyper reactive |
| Specific Phobias: phobic stimuli: response time | faster |
| Specific Phobias: post exposure therapy: amygdala | less reactive |
| Specific Phobias: post exposure therapy: insula | less reactive |
| Specific Phobias: post exposure therapy: dACC | less reactive |
| Specific Phobias: post exposure therapy: vmPFC | increased activity |
| Panic Disorder: masked faces with fear: amygdala | hyper reactivity |
| Panic Disorder: masked faces with happy: amygdala | hyper reactivity |
| Panic Disorder: masked faces with fear: vmPFC | hypo reactivity |
| Panic Disorder: masked faces with happy: vmPFC | hypo reactivity |
| Panic Disoder: reappraisal: dlPFC | less activity |