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Day 1
ED
| Question | Answer |
|---|---|
| Physiology: Blood flows from hypgastric area into the ercitile chambers? | Intracavernosal Space |
| Physiology: the chemical responsible for mainteaining relaxation of Intracavernosal Trabeculae and Influx of blood | cGMP |
| Drugs? should not receive Nitrates within 24 hours | Sildenafil (Viagra), Vardenafil (Levitra) -- Renal or Hepatic impairment = wait longer (48 hr?) |
| Drugs ADR - Visual effects is blue vision | Sildenafil. Other two are not reported |
| Drugs? Must wait for 48 hr before giving Nitrates | Tadalafil (Cialis) |
| Drug? No Alpha Blocker within 4 hr if dose > 25mg | Sidenafil |
| Dose of Sildenafil (Viagra) | 25-50mg 1hr before sex (QD). MD (25-100mg PO QD) |
| Efficacy of Sildenafil (Viagra) | Men w/ organic, psychogenic or mixed ED. DM, Protage Cancer |
| Does any significant link between Sildenafil and cardiac event? | NO but pt with Heart problem must be caution |
| Dose of Vardenafil (Levitra) | 10 mg PO 1h b/f sex (Max 20) - As effective as Sildenafil |
| Caution of Vardenafil (Levitra) | High fat meals, QT prolongation. Must stable on AAA before starting on Vardenafil |
| Dosage of Tadelafil (Cialis) | 2.5 - 10 (max 20) wait 1hr b/f sex |
| What AAA is approved to use with Tadelafil (Cialis)? | Tamsulosin (still not within 4 hrs) |
| When to give Teststerone with Sildenafil? | Concentration <400 mg/dL. Non-responders to Sildenafil only and Hypogonadal (Best = use Gel) |
| Priapism | Erection lasting longer than 4 hrs (require medical attention STAT) |
| Most beneficial in young pts with traumatic arterial lesions | Vascular Surgery |
| Brand name of Intraurethral Alprostadil | Muse (125-1000mcg) - max 2 doses (pellets)/24hr |
| Intraurethral vs Injection (Alprostadil): less fibrosis and priapism | Intraurethral |
| Brand name of Alprostadil Injection | (Caverjet, Edex) - (start: 1.25-2.5 mcg, Avg: 1.25-20 mcg) - Max 3 dose/wk - 24 hr apart |
| CI of Alprostadil Injection | Bleeding disorder/anticoagulation (Warfarin, LMWH, PLAVIX, ASA) |
| ADR of Alprostadil Injection | Fibrosis and Priapism |
| What consideration when using Testtosterone Esters (Enanthate, Cypionate) | Oily base, Deep IM, Inject every 1-3 wks, Fluctuation serum concentration, energy, mood, libido |
| What has steady concentration of Testosterone over 24 hrs | Patch and Gel |
| What has normal serum concentration obtained within month | Gel |
| Testosterone only work when.... | Hypogonadism. (Must get testosterone level blood test first) |
Created by:
_Tom_
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