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corticolimbic circut
anatomy
| Term | Definition |
|---|---|
| amygdala | circuit hub |
| thalamus | sub cortical route to the amygdala |
| pulvinar | thalamic nuclei related to vision |
| dorsal visual stream | "where" stream |
| ventral visual stream | "what" stream |
| paraventricular nucleus | innervated by the CeA and leads to downstream endocrine changes |
| Nucleus Reticularis Pontis Caudalis | related to fear potentiated startle response |
| Periaquiductal gray | associated with the freezing response |
| Parabrachial Nucleus | activation: increased respiration and nociceptive input to CeA |
| Dorsal Motor Nucleus of the Vagus | activation changes resting heart rate |
| vagal tone | resting heart rate |
| ventral tegmental area | brainstem region of dopamine production |
| dorsal raphe | brainstem nuclei for serotonin production |
| locus ceruleus | brainstem nuclei for norepinephrine production |
| nucleus basalis of meynart (NBM) | cholinergic neurons of the basal forebrain |
| bed nucleus of the stria terminalis (BNST) | drives the "anxiety" response |
| insula | cortical region, interoception |
| hippocampal formation | made up of the entorhinal ctx, perirhinal ctx, parahippocampal ctx, hippocampus |
| medial pre frontal cortex | region of higher order behavioral regulation |
| dmPFC | inhibts the amygdla via top down processing |
| vmPFC | conscious appraisal of the situation, information integration |
| dorsal anterior cingulate cortex (dAcc) | conflict monitoring |
| vlPFC | situation reappraisal |
| dlPFC | planning and execution |
| PVN, brainstem, NBM | regions of direct amygdala output |
| insula, HP formation, PFC | regions of indirect amygdala output |
| hypothalamic, pituitary, adrenal axis. A stress response that culminates in the release of cortisol | HPA axis |