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Voc. II
Hormone Synthesis
| Term | Definition |
|---|---|
| Alternate Splicing | It is the way of introducing diversity to the gene products of transcription by creating multiple protein products from the same DNA sequence. |
| Coactivators or corepressors | Molecules that help the transcription factors bind to the DNA in order for gene transcription to occur. |
| Codon | A triplet of adjacent nucleotides in the messenger RNA chain that codes for a specific amino acid in the synthesis of a protein molecule. |
| Cytokines | Any of a class of immune-regulatory proteins that are secreted by cells especially of the immune system. |
| Exocytosis | The release of cellular substances by vesicles that fuse with the plasma membrane and transport the substances out of the cell. |
| Exon | A segment of a DNA or RNA molecule containing information coding for a protein or peptide sequence. |
| Glycosylation | The process by which sugars are chemically attached to proteins to form glycoproteins. |
| Hormone convertases | Enzymes that are packaged into secretory vesicles that bud off from the Golgi stacks. |
| Introns | A noncoding segment in the DNA that interrupts a gene-coding segment of the DNA. |
| Metabolic clearance rate | Is the same as the half-life of a hormone in blood which is the period of time needed for the hormone’s concentration to be reduced by half. |
| Neurotransmitter | A chemical substance that is produced and secreted by a neuron then diffuses through the synapse to excite or inhibit another neuron. |
| Nucleosomes | Is a section of DNA that is wrapped around a core of proteins called histones. |
| Prohormone | A substance that is a precursor to a hormone, usually having minimal hormonal effect by itself. |
| Promoter | Is a region of DNA that initiates transcription of a particular gene. |
| Secretogranins | Large acidic proteins that sort hormones into immature vesicles and process them for secretion. |
| Signal transduction | Conversion of a hormonal message to cellular responses. |
| SNARE | Proteins in the membrane of vesicles and plasma membrane that facilitate secretion of peptide hormones to outside of the cell by exocytosis. |
| Splicing | The removal of introns and the joining of exons from mRNA precursors. |
| Transcription factors | Nuclear proteins, which regulate sites that are upstream from the promoter and stimulate or repress gene transcription. |