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Pharm(Mediola)
depression/bipolar disorder
| unit 10/11 | unit 10/11 | unit10/11 | unit10/11 |
|---|---|---|---|
| drug classifications for depression | tricyclic antidepressants(TCA), selective serotonin reuptake inhibitors(SSRI), monoamine oxidase inhibitors(MAO-I), atypical agents | Indications for antidepressants | major depression/anxiety disorder, obsessive compulsive disorder(OCD), pain management/smoking cessation |
| tricyclic antidepressants(TCA) | Elavil | TCA indications | major depression, OCD |
| side effects of TCA | orthostatic hypotension, sedation | selective serotonin reuptake inhibitors(SSRI) drugs | Prozac, Paxil, Zoloft |
| side effects for SSRI | sexual dysfunction, headache, insomnia/sedation | indications for SSRI | major depression, OCD |
| monoamine oxidase inhibitors(MAO-I) drugs | Nardil | side effects for nardil | many drug and food interactions, hepatotoxicity |
| indications for nardil | depression unresponsive to other agents | atypical agents | Desyrel, Wellbutrin |
| indications for atypical agents | depression and may be used for specific actions | side effects of Desyrel & Wellbutrin | Desyrel: sedation , Wellbutrin: decrease seizure threshold |
| drugs for bipolar disorder | lithium, tegretol | indications for lithium or tegretol | bipolar disorder, depression |
| precaut/contra for lithium | use with ace-1, calcium channel blockers, NSAIDS = increases lithium levels | side effects for lithium | toxicity - confusion, tremor, seizure, cardiac dysrhythmias |
| therapeutic drug level for lithium | 0.5 - 1.5 mEq/L | therapeutic effects of lithium/tegretol | decrease cycles of mania/depression |