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Ch. 25 questions

Viral Diseases of the Respiratory Tract

What is the principal cause of the common cold? rhinoviruses
If you have 113 bouts of rhinovirus, will you be immune for the rest of your life? no--immunity lasts only one year
what is the major site of infection for adenoviruses? upper respiratory tract
How many adenoviral infections can an individual experience? at least 50
What are the two surface virulence proteins of the influenza virus? neuraminidase and hemagglutinin
What is the function of neuraminidase and hemagglutinin? neuraminidase--breaks down protective mucous layer that lines the throat--hemagglutinin--attaches to ciliated epithelial cells in throat--virus can enter and kill cells
Pandemic worldwide epidemic
Antigenic drift mutational change in hemagglutinin and neuraminidase genes
Antigenic shift complete hemagglutinin gene change
what is the cause of death in those who have influenza? cause of death in those with influenza is secondary to bacterial pneumonia
How do amantadine, ribavirin, and zanamivir function? inhibit uncoating, viral RNA replication, and jeuraminidase, respectively
What is the overall effectiveness of influenza vaccines? overall effectiveness of influenza vaccines in 70-80%--save many lives
Parotitis inflammation of the parotid(salivary) glands caused by mumps virus
Orchitis inflammation of the testes caused by mumps virus
What two diseases are caused by varicella-zoster virus, and how are they transmitted? chicken pox and shingles--chicken pox--transmitted via resp tracct droplets--shingles--latent--occurs when endogenous viruses reactivated
Who is at risk for rubella virus? a fetus, especially during the first trimester, is at risk for rubella virus
Who is given rubella vaccine? general population given rubella vaccine to protect the unborn
What is MMR? single dose vaccine for mumps, measles, and rubella
List the alternative name for measles seven-day measles
List the alternative name for rubella 3-day measles or German measles
Who is at risk for respiratory syncytial virus (RSV)? infants and young children
What needs to be done when an RSV case appears in a neonatal ward? infected children isolated and treated with ribavirin via respirator--health-care workers should wear protective equipment
What two tissue types are predominately infected by poliovirus? alimentary canal and neurons in the spinal column
How do we prevent paralytic polio? vaccination with the salk(killed virus) and Sabin(live-attenuated virus) vaccines
Created by: heatherlvn