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Lecture 11
Lecture 11: The Endocrine System
| Question | Answer |
|---|---|
| Hormone | acts at long distances form where it has been released |
| Autocrine Molecules | act upon the same cells that secrete them |
| Paracrine Molecules | act on different cells from the ones that secrete them but act at a very short distance |
| Skin | Vitamin D3, Small intestine |
| Adrenal cortex | Glucocorticoids, aldosterone, androgens/ liver, kidneys, other tissue |
| Adrenal Medulla | Epinepherine/ heart and blood vessels |
| Pancreas (Islet of Langherans) | Insulin, glucagon/ liver, adipose tissue, many organs |
| Ovaries | estradiol, progesterone/ female reproductive tract and mammary gland |
| Testis | Testosterone/ prostate, seminal vesicles, muscle, and bone |
| Pineal Gland | Melatonin/ hypothalamus and anterior pituitary |
| Thyroid | T4, T3, Calcitonin/ most organs |
| Parathyroid | PTH/ bone, small intestine, kidney |
| Adenohypophysis | Trophic hormones/ other endocrine glands and organs |
| Neurohypophysis | Oxytocin, Vasopressin (ADH)/ uterus, mammary gland, kidneys, and blood vessels |
| Hypothalamus | Releasing and Inhibiting hormones/ Anterior pituitary |
| Kidneys | Erythropietin/ bone marrow |
| Heart | Atrial natriuretic peptide/ kidneys |
| Prehormones | non bioactivated hormones |
| Sensitization | up-regulation, an increase in the number of receptors |
| Desensitization | down-regulation, decrease in the number of receptors |
| Affinity | the concentration of hormone needed to occupy 50% of the receptor |
| Sensitivity | hormone concentration required to produce a half-maximal physiological response |