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Responses to Antigen
MTSU Stegall-Faulk Anatomy 2
| Term | Definition |
|---|---|
| antigens | any molecule capable of binding to an antibody and triggering an immune response |
| epitopes | evoke an immune response |
| antibodies | proteins that react with antigens in the plasma or other body fluids |
| non-specific resistance | the ability to react with many different types of foreign substances. |
| physical resistance | the integument, mucous membranes of the respiratory and digestive tracts, tears, saliva, and perspiration. |
| antimicrobial resistance | interferons and complement system |
| interferons | produced by macrophages, lymphocytes, and infected cells. stops the virus from replications. |
| complement system | plasma protiens that complement the activities of both non-specific and specific responses. |
| four methods of antigen destruction | inflammation, immune clearence, phagocytosis, and cytolysis. |
| inflammation | A-> binds to histamines and mast cells |
| immune clearance | Binds to Ag-Ab complexes to RBC's-> liver nd spleen->phygocytes remove Ag-Ab complex |
| Phagocytosis | coats bacteria, virius, and pathogens-> opsinization-> phagocytosis |
| cytolysis | split C5 into A and B-> binds to C6,7,and 8-> the complex binds ring of C9 molecules-> membrane attack complex-> cytolysis. ring creates an opening in the target cell until cell ruptures. |
| inflammatory response | swelling, heat, redness, and pain. |
| diapedesis | WBC squeeze between call walls to get into the tissue |
| purpose of the inflammatory response | isolate the site of infection or injury, destroy the pathogen, and begin the healing process. |