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Psychopharm102
MH nursing
Question | Answer |
---|---|
What are the functions of acetylcholine? | Sleep, arousal, pain, movement, memory |
Increased levels of acetylcholine? Decreased? | Depression-----Alzheimer's, Huntington's, Parkinson's |
What are the functions of norepinephrine? | mood, cognition, sleep/arousal, CV function, perception |
Decreased levels of norepi? Increased levels? | Depression-----mania, anxiety, schizophrenia |
What are the functions of Dopamine? | movement, coordination, emotions |
Increased levels of dopamine? Decreased? | Mania and schizo------Parkinson's, Depression |
What are the functions of serotonin? | sleep, arousal, libido, appetite, aggression, pain, judgement |
Decreased levels of serotonin? Increased levels? | depression--------anxiety |
What are the functions of GABA? | calms, reduces aggression |
Decreased levels of GABA? Increased? | Anxiety, Huntington's, schizo, epilepsy-------sedation, anti-convulsant |
Endorphins | internal opiates--play a role in pain modulation--morphine-like action |
Anticholinergic use: | EPSE of antipsychotics SLUDGE (sedation, lethargy, urinary retention, dry mouth, GI upset, and energy loss) CI with glaucoma |
Neuroleptic malignant syndrome: | from antipsychotic tox, life threatening SXS: high temp (107), increased HR, diaphoresis and risk for organ failure Clozapine--WBC and drooling |
SEs of TCAs and SSRIs | HA, drowsiness, hypotension, urinary retention, EPSE, photosens. can use for cardiac dysrhythmias Luvox and Anafranil used for OCD Effective in 7-10 days and therapeutic within 3-4 weeks |
Antianxiety uses and side effects (need to wean) | use: relaxant, seizure reduction, alcohol w/d, ST use only! tolerance can occur within 3-4 weeks- SE: drwosy, low BP, confusion, safety BuSpar is non narcotic Toxic: R depression, CI with pregnancy/BF, hepatic disease, MAOs W/D--dep., paranoia, deliri |
Lithium use, SE, blood levels, interventions | use: Bipolar SE: flu like, diarrhea, N, V, ataxia, cranial nerve problems--can combine Interv: monitor diet--NA Blood level: 0.6-1.2 if higher=fatal tox: vomiting, diarrhea, ataxia, confusion (CNS) |
SED/HYP use and SEs | sleep, pre-op SE: addiction, drowsiness, excitement |
Anticonvulsants use/ SEs | mood stabilizer (Bipolar, Depression) check labs often (liver and kidney) May decrease effectiveness of BC pills toxic: diplopia, blurry vision, agranulocytosis, anemia, liver failure |
Inderal | panic disorders |
ECT drugs | Anectin, Quillicin, Brevital |
Antipsychotics use: | major tranquilizers, decrease dopamine at receptor sites psychoses, MedSurg-hiccups, antiemetics Typical or Atypical |
Antipsychotic SEs: | Akinesia:absence of muscle movement Akathasia: anxious, pacing, restless Dystonia: tight muscles, uncoord., jerking PseudoP: shuffling gait, flat affect Tardive Dysk: facial muscles, preventable lowers seizure threshold and wt gain/dry mouth decreas |
MAO SE: | prevents norepi and serotonin from breaking down SE: hypertensive crisis, HA, high BP Do not give within 2 wks of other antidep. Need low tyramine diet!! not first line med |
Limbic system | emotional brain |
NTs | brain chemicals that transmit electrical impulses, essential to emotions and behavior Cross synapse and allow impulse or block it, reuptake--stores for further use |